PMID: 3760896Sep 1, 1986Paper

Quantitative sweat test in diabetics with neuropathic foot lesions

Journal of Neurology, Neurosurgery, and Psychiatry
M E Ahmed, P M Le Quesne

Abstract

The volume of sweat produced by axon reflex stimulation using acetylcholine was measured in one foot each of 35 control subjects and 52 feet of 37 diabetic patients (28 with neuropathic ulceration, 11 with Charcot arthropathy, nine with somatic neuropathy but no foot lesion and four with no evidence of somatic neuropathy). In controls, the volume of sweat was greater in males than females. A flare response was seen in 94% of control feet. In diabetics, the volume of sweat was within the control range in 17 feet, increased in one, reduced in seven, and absent in 27. Sweating was absent in 75% of feet with a neuropathic ulcer; a flare response was absent in 86% of them. Sweating was only absent in 36% of feet with Charcot arthropathy and was increased in one, whereas the flare response was absent in all. Autonomic cardiovascular reflexes were more frequently abnormal than the sweat test; sweating was absent in only one patient with normal cardiovascular reflexes.

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Citations

Oct 1, 1994·Journal of Neurology·Y ManoR F Mayer
Jun 1, 1995·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·T J BergR R Abraham
Oct 29, 1998·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·M KiharaM Takahashi
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May 1, 1992·Diabetic Medicine : a Journal of the British Diabetic Association·M D Flynn, J E Tooke
Jan 1, 1989·Journal of Neurology, Neurosurgery, and Psychiatry·Z AliC J Fowler
Jul 1, 1990·Journal of Neurology, Neurosurgery, and Psychiatry·P M Le QuesneN Parkhouse
Oct 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·D M LevyR R Abraham
May 1, 1988·Diabetes/metabolism Reviews·A Vinik, B Mitchell
Apr 18, 2018·The Journal of Bone and Joint Surgery. American Volume·Andrew Dodd, Timothy R Daniels
Oct 1, 1986·Journal of Neurology, Neurosurgery, and Psychiatry·P M Le Quesne, C J Fowler
Jan 1, 1988·Journal of Neurology, Neurosurgery, and Psychiatry·N Parkhouse, P M Le Quesne
Nov 29, 2005·Foot & Ankle International·Fabio BatistaCaio A S Nery

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