Quantitative transrectal shear wave elastography undergoing salvage extraperitoneal laparoscopic radical prostatectomy following failed radiotherapy

Surgical Endoscopy
Cheng WeiGhulam Nabi

Abstract

To evaluate pre-surgical quantitative transrectal shear wave elastography (SWE) in the detection and characterisation of radioresistant prostate cancer. Twelve men with recurrent prostate cancer following external beam radiotherapy were included in a prospective protocol-driven study. All underwent MR imaging and quantitative shear wave elastographic assessment of recurrent disease prior to salvage laparoscopic radical prostatectomy procedures. Images were used to construct 3D mold printing and histopathological processing of surgical specimen. Statistical analyses including ROC were generated using software programmes. There were 48 cancer foci identified on final histopathology using patient-specific mold-based approach in 12 patients. Mean number of lesion was 3.4 (range 2-4). Quantitative transrectal SWE showed a sensitivity and specificity 0.77 (95% CI 0.627-0.880) and 0.82 (95% CI 0.642-0.942), respectively. The diagnostic accuracy increased with increasing size of the lesions with overall AUC of 0.89. In our series, quantitative transrectal SWE showed a good diagnostic accuracy in the detection and characterisation of recurrent prostate cancer following failed radiotherapy treatment. These findings may help in targeting ...Continue Reading

References

Sep 24, 2002·International Journal of Radiation Oncology, Biology, Physics·Torunn I YockJohn J Coen
Nov 5, 2003·Ultrasound in Medicine & Biology·J BercoffM Meunier
Mar 18, 2004·JAMA : the Journal of the American Medical Association·Andrew J StephensonKevin M Slawin
May 14, 2004·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Jérémy BercoffMathias Fink
Sep 21, 2007·International Journal of Radiation Oncology, Biology, Physics·Masoom A HaiderMichael Milosevic
Dec 20, 2007·Ultrasound Quarterly·Brian Stephen Garra
May 28, 2010·Radiology·Alexandra AthanasiouSylvia Neuenschwander
Feb 7, 2012·Current Medical Imaging Reviews·Armen SarvazyanBrian S Garra
Apr 27, 2012·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Richard G Barr
Sep 25, 2012·The Journal of Urology·Samuel D KaffenbergerJoseph A Smith
Apr 24, 2013·Diagnostic and Interventional Imaging·J-M CorreasO Hélénon
May 21, 2014·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Sungmin WooSeung Hyup Kim
Jan 20, 2015·Radiology·Jean-Michel CorreasRichard G Barr
Aug 28, 2016·Ultrasound in Medicine & Biology·Richard G BarrChristoph F Dietrich

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