Quercetin: a potential drug to reverse multidrug resistance

Life Sciences
Chen ChenChunyan Ji

Abstract

This review centers on recent findings with respect to modulating cancer multidrug resistance (MDR) with the well-known flavonoid quercetin. After a short introduction of quercetin, major in vitro and in vivo findings are summarized showing that quercetin is a MDR modulator and thus a potential chemosensitizer. Finally, we contemplate future prospects of modulating MDR in the clinic.

References

Dec 15, 1987·The Biochemical Journal·V D BokkenheuserJ Winter
Aug 15, 1995·Proceedings of the National Academy of Sciences of the United States of America·G J ZamanP Borst
Nov 22, 1996·Biochemical Pharmacology·K Zhang, K P Wong
Aug 1, 1997·American Journal of Epidemiology·P KnektA Aromaa
Feb 7, 1998·European Journal of Biochemistry·A B Shapiro, V Ling
Jan 1, 1997·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·P C Hollman, M B Katan
Aug 26, 1998·Proceedings of the National Academy of Sciences of the United States of America·G ConseilA Di Pietro
Dec 23, 1998·Proceedings of the National Academy of Sciences of the United States of America·L A DoyleD D Ross
Jan 6, 2000·Archives of Biochemistry and Biophysics·H ShihL C Quattrochi
May 17, 2000·European Journal of Pharmacology·Y MitsunagaY Sawada
Oct 18, 2000·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·R Krishna, L D Mayer
Oct 29, 2000·Cancer Chemotherapy and Pharmacology·R De VincenzoG Scambia
Aug 11, 2001·Cellular and Molecular Life Sciences : CMLS·T LitmanS E Bates
May 25, 2002·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·E J OliveiraM H Grant
Oct 9, 2002·Current Protein & Peptide Science·Karin F K Ejendal, Christine A Hrycyna
Dec 18, 2002·Drug Metabolism and Disposition : the Biological Fate of Chemicals·Elaine M LeslieSusan P C Cole
Jan 18, 2003·Journal of Pharmaceutical Sciences·Hang NguyenMarilyn E Morris
Aug 19, 2003·Archives of Biochemistry and Biophysics·Kaeko Murota, Junji Terao
Oct 25, 2003·Oncogene·Suresh V AmbudkarMichael M Gottesman
Nov 25, 2003·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Yong LiuMing Hu
Dec 31, 2003·Life Sciences·Yao-Horng WangYu-Chi Hou
Mar 17, 2004·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Jun-Shik ChoiYoun-Chul Kim
Mar 30, 2004·Biochemical and Biophysical Research Communications·Hiran C CoorayMargery A Barrand
Apr 23, 2004·Molecular Pharmacology·Shuzhong ZhangMarilyn E Morris
Aug 28, 2004·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Theoharis C Theoharides, Leonard Bielory
Jan 13, 2005·Canadian Journal of Physiology and Pharmacology·S KothanS Mankhetkorn
Mar 3, 2005·The Journal of Nutritional Biochemistry·Woo K KimJung H Y Park
Apr 14, 2005·Biochemical Pharmacology·J Jakubowicz-GilM Kandefer-Szerszeń
Apr 15, 2005·Journal of Chemotherapy·P LimtrakulK Pintha
Apr 20, 2005·The Journal of Surgical Research·S Halide AkbasTomris Ozben
Jun 11, 2005·Pharmaceutical Research·Xiao ChenMoses S S Chow
Jul 23, 2005·Free Radical Research·G WilliamsonJ Terao
Aug 24, 2005·Archives of Pharmacal Research·Soo Yeon ChungHwa Jeong Lee
Nov 18, 2005·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Young Jin MoonMarilyn E Morris
Mar 7, 2006·International Journal of Pharmaceutics·Sang-Chul ShinXiuguo Li
May 10, 2006·Biochemistry·Alena SiarheyevaClemens Glaubitz
Jul 6, 2006·Trends in Pharmacological Sciences·Susan P C Cole, Roger G Deeley

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Citations

Apr 23, 2013·Applied Biochemistry and Biotechnology·Sílvia MartinsSolange I Mussatto
Feb 21, 2013·European Journal of Clinical Nutrition·S-Y WangZ-Q Liu
Mar 21, 2012·Nutrition and Cancer·Zora DjuricIkuko Kato
Nov 13, 2013·Journal of Asian Natural Products Research·Nai-Hao LuYi-Yuan Peng
Aug 9, 2012·Antioxidants & Redox Signaling·Balachandran S VinodRuby John Anto
Sep 11, 2014·Cellular Oncology (Dordrecht)·Vivek V DhawanMangal S Nagarsenker
Dec 3, 2014·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Jan Czepas, Krzysztof Gwoździński
Dec 7, 2011·Critical Reviews in Clinical Laboratory Sciences·Miguel AsensiJosé M Estrela
Jun 1, 2014·Fitoterapia·A Zholobenko, M Modriansky
Feb 5, 2015·Artificial Cells, Nanomedicine, and Biotechnology·Juhong RanHaiying Zhang
Apr 24, 2015·Journal of Medicinal Chemistry·Inês L MartinsAlexandra M M Antunes
Apr 5, 2011·Chemico-biological Interactions·Xiao-Wu ChenShu-Feng Zhou
Oct 11, 2015·The Journal of Pharmacy and Pharmacology·Xinru LiGuiling Li
Oct 8, 2014·Analytical Chemistry·Dwayne A L VickersSoojung Claire Hur
Mar 5, 2016·Nutrition and Cancer·Ana Filipa BritoMaria Filomena Botelho
Nov 26, 2011·British Journal of Clinical Pharmacology·Lan-Xiang WuHong-Hao Zhou
Jun 4, 2014·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Ilaria PelusoMaura Palmery
Sep 24, 2015·Fitoterapia·Gabriele D'Andrea
Jul 15, 2015·Neurochemistry International·Federico DajasLucía Vaamonde
Jun 26, 2012·Biochimica Et Biophysica Acta·Jun XiaZhiwei Wang
Jun 4, 2011·Life Sciences·Nathália G AmadoJosé G Abreu
Nov 29, 2011·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·Lan-Xiang WuHong-Hao Zhou
Jul 24, 2012·Journal of Ethnopharmacology·Federico Dajas
Oct 23, 2012·Biochimica Et Biophysica Acta·Allison DerenneErik Goormaghtigh
Nov 21, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Lauren L ZaminGuido Lenz
May 8, 2013·Journal of Controlled Release : Official Journal of the Controlled Release Society·Kaushik ThankiSanyog Jain
Feb 28, 2015·Food Chemistry·Seyed Fazel NabaviSeyed Mohammad Nabavi
May 12, 2016·The Journal of Pharmacy and Pharmacology·Osamu KimuraTetsuya Endo
Jul 1, 2016·Acta Veterinaria Scandinavica·Ramona BabosovaMonika Martiniakova
Nov 5, 2014·BMC Complementary and Alternative Medicine·Haixing YangYonghua Wang
Jul 12, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Solida LongMadalena M M Pinto
Jan 6, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Carole Nicco, Frédéric Batteux

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