Quintessential Culture-Negative Endocarditis

The Canadian Journal of Cardiology
Yoav KeynanPhilippe Lagacé-Wiens

Abstract

Bartonella spp are important causes of culture-negative endocarditis, generally causing a subacute insidious form of endocarditis, often leading to a delay in diagnosis. Most patients have fever and often present with signs and symptoms of heart failure. The diagnosis is frequently established only on meticulous examination of the resected heart valve with the polymerase chain reaction technique. We present a case of B quintana mitral and aortic valve endocarditis with associated severe valvular insufficiency and decompensated heart failure precipitated by Streptococcus pneumoniae bacteremia, necessitating urgent surgical valve replacement. Pathologic examination of the valve complemented by serologic and molecular testing established the surprising diagnosis of B quintana endocarditis.

References

Nov 30, 2004·The Lancet Infectious Diseases·Werner C AlbrichHelmut Albrecht
Feb 24, 2006·Emerging Infectious Diseases·Cédric FoucaultDidier Raoult
May 6, 2008·Diagnostic Microbiology and Infectious Disease·Jens DreierKnut Kleesiek
Jun 15, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Pierre-Edouard FournierDidier Raoult

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Citations

Feb 23, 2019·The American Journal of Tropical Medicine and Hygiene·John C LamBonnie L Meatherall

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