Abstract
The conjugational transfer efficiency of 41 wild-type R-plasmids was studied in Escherichia coli K-12. Type I R-plasmids were transferred at comparatively high and rather uniform frequencies, whereas type F R-plasmids showed less uniform and, on average, somewhat lower transfer frequencies. R-plasmids not mediating sensitivity to F-, I-, or N-specific phages showed moderate transfer frequencies, and type N R-plasmids showed very low transfer frequencies. Various lines of evidence suggest that a well-expressed, but functionally inefficient, conjugation apparatus is the cause of the poor transfer of type N R-plasmids in liquid medium. Nalidixic acid efficiently inhibited transfer of type I and particularly type F R-plasmids, whereas the transfer of type N plasmids was resistant to the drug. Type F and type I plasmids appear to depend on at least one host function for their transfer, namely, the nalidixic acid-sensitive reaction in vegetative chromosome replication, whereas type N plasmids are independent of this function.
References
Jul 1, 1977·Journal of Bacteriology·L G Burman
Apr 15, 1976·Nature·G C Crumplin, J T Smith
Jul 1, 1975·Journal of Bacteriology·L G Burman
Jul 10, 1975·Molecular & General Genetics : MGG·S Dennison, S Baumberg
Jul 15, 1972·Lancet·E Roe, R J Jones
Oct 1, 1973·Antimicrobial Agents and Chemotherapy·G J BourguignonR Sternglanz
Jan 1, 1968·Molecular & General Genetics : MGG·S E BreslerA A Lukjaniec-Blinkova
Dec 1, 1973·Journal of Bacteriology·R G Fenwick, R Curtiss
Jun 28, 1974·Nature·P BrodtR Iyer
Sep 14, 1967·Journal of Molecular Biology·S D Barbour
Oct 28, 1967·Nature·A M LawnN Datta
Oct 1, 1967·Journal of General Microbiology·Y NishimuraY Hirota
Jan 1, 1969·Journal of Bacteriology·J V BoyleW A Goss
Jan 1, 1968·Cold Spring Harbor Symposia on Quantitative Biology·K W Fisher, M B Fisher
Jan 1, 1968·Cold Spring Harbor Symposia on Quantitative Biology·A CohenH I Adler
Jul 1, 1969·Journal of Bacteriology·M W Hane, T H Wood
Jun 1, 1970·Journal of Bacteriology·N Bouck, E A Adelberg
Jan 1, 1970·Molecular & General Genetics : MGG·J E Dowman, G G Meynell
Nov 26, 1971·Nature·N Datta, R W Hedges
Apr 1, 1972·Virology·H KhatoonV N Iyer
Nov 1, 1965·Genetical Research·S Hollom, R H Pritchard
Jan 1, 1971·Journal of Bacteriology·M W Hane
May 27, 1967·Nature·E Meynell, N Datta
Apr 1, 1965·Journal of Bacteriology·W A GOSST M COOK
Citations
Jan 24, 2013·Epidemiology and Infection·V V VolkovaY T Grohn
Jan 1, 1988·Pharmacotherapy·M LeBel
Apr 2, 2008·Antimicrobial Agents and Chemotherapy·Keith MillerIan Chopra
Dec 1, 1989·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J S Wolfson
Jun 1, 1995·Genitourinary Medicine·K M KamM M Cheung
Jul 23, 2019·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Mariem SaidaniMarisa Haenni
Apr 1, 1989·Journal of Bacteriology·D C HooperM N Swartz
Oct 1, 1985·Antimicrobial Agents and Chemotherapy·J S Wolfson, D C Hooper
Oct 1, 1989·Clinical Microbiology Reviews·J S Wolfson, D C Hooper
Jan 1, 1993·International Journal of Antimicrobial Agents·A Bryskier
Apr 1, 1987·Antimicrobial Agents and Chemotherapy·J Weisser, B Wiedemann
Feb 28, 2002·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Apostolos GeorgopoulosWolfgang Graninger