Rabbit as a reproductive model for human health

Reproduction : the Official Journal of the Society for the Study of Fertility
Bernd FischerV Duranthon

Abstract

The renaissance of the laboratory rabbit as a reproductive model for human health is closely related to the growing evidence of periconceptional metabolic programming and its determining effects on offspring and adult health. Advantages of rabbit reproduction are the exact timing of fertilization and pregnancy stages, high cell numbers and yield in blastocysts, relatively late implantation at a time when gastrulation is already proceeding, detailed morphologic and molecular knowledge on gastrulation stages, and a hemochorial placenta structured similarly to the human placenta. To understand, for example, the mechanisms of periconceptional programming and its effects on metabolic health in adulthood, these advantages help to elucidate even subtle changes in metabolism and development during the pre- and peri-implantation period and during gastrulation in individual embryos. Gastrulation represents a central turning point in ontogenesis in which a limited number of cells program the development of the three germ layers and, hence, the embryo proper. Newly developed transgenic and molecular tools offer promising chances for further scientific progress to be attained with this reproductive model species.

References

Dec 1, 1992·Developmental Dynamics : an Official Publication of the American Association of Anatomists·V Hamburger, H L Hamilton
May 1, 1990·Molecular Reproduction and Development·N A TelfordG A Schultz
Jun 1, 1990·The Anatomical Record·B S Williams, J D Biggers
Feb 1, 1985·Journal of Dairy Science·L M HoudebineJ L Servely
Sep 1, 1988·Teratology·W Lenz
Nov 1, 1986·Journal of Reproduction and Fertility·B FischerL C Busch
Jul 1, 1995·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·M BaranyiB Ribadeau-Dumas
May 1, 1997·Reviews of Reproduction·P L Kaye
Feb 13, 1999·Cell·R S Beddington, E J Robertson
Jun 6, 2000·Advanced Drug Delivery Reviews·A C Enders, T N Blankenship
Dec 2, 2000·Reproductive Toxicology·R H Foote, E W Carney
Feb 15, 2001·Genesis : the Journal of Genetics and Development·C Viebahn
Feb 24, 2001·Annals of the New York Academy of Sciences·H M Beier
Jun 18, 2002·Nature Medicine·Norikazu MaedaYuji Matsuzawa
Nov 22, 2002·Biology of Reproduction·Sylviane Pacheco-TrigonVéronique Duranthon
Mar 4, 2003·Reproduction : the Official Journal of the Society for the Study of Fertility·K E Markham, P L Kaye
Feb 1, 1960·Journal of Reproduction and Fertility·C E ADAMS
Apr 28, 1962·Lancet·G S SOMERS
Aug 1, 1964·Journal of Reproduction and Fertility·M F HAY
Oct 14, 2004·Development Genes and Evolution·Jan IdkowiakChristoph Viebahn
Oct 29, 2004·Reproduction : the Official Journal of the Society for the Study of Fertility·Anne Navarrete SantosBernd Fischer
Oct 29, 2004·Reproduction : the Official Journal of the Society for the Study of Fertility·Anne Navarrete SantosBernd Fischer
Jan 27, 2005·American Journal of Physiology. Endocrinology and Metabolism·David J FlintPaul A Kelly
Nov 3, 2005·Reproduction : the Official Journal of the Society for the Study of Fertility·M MitchellR J Norman
Mar 12, 2008·Histochemistry and Cell Biology·Thomas SchmidtBernd Fischer

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Citations

Dec 21, 2013·PloS One·Estrella Jiménez-TrigosFrancisco Marco-Jiménez
May 23, 2014·Journal of Developmental Origins of Health and Disease·Pauline LéveilléPascale Chavatte-Palmer
Feb 22, 2013·Reproduction : the Official Journal of the Society for the Study of Fertility·Pouneh MaraghechiElen Gócza
Feb 19, 2014·Reproduction : the Official Journal of the Society for the Study of Fertility·M D Saenz-de-JuanoJ S Vicente
Jun 6, 2014·Journal of Developmental Origins of Health and Disease·C DupontP Chavatte-Palmer
Jul 1, 2014·Acta histochemica·Arely Anaya-HernándezEstela Cuevas
Jan 16, 2013·The Journal of Steroid Biochemistry and Molecular Biology·Laura Torres-RoviraAntonio Gonzalez-Bulnes
Jan 21, 2016·Mediators of Inflammation·Fabiana NevesPedro J Esteves
Feb 3, 2016·Reproduction : the Official Journal of the Society for the Study of Fertility·Jacqueline GürkeAnne Navarrete Santos
Mar 2, 2013·American Journal of Reproductive Immunology : AJRI·Elizabeth A Bonney
Aug 14, 2015·Journal of Developmental Origins of Health and Disease·J López-TelloP G Rebollar
Jun 23, 2015·Reproductive Biomedicine Online·Sergi NovoCarme Nogués
Jun 9, 2015·Reproductive Toxicology·Karin Sørig HougaardFlemming R Cassee
Jun 9, 2016·Endocrine Research·Julia Rodríguez-CastelánEstela Cuevas-Romero
Jun 18, 2016·International Journal of Environmental Research and Public Health·Pascale Chavatte-PalmerDelphine Rousseau-Ralliard
Nov 9, 2016·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Maria Desemparats Saenz-de-JuanoJose Salvador Vicente
Feb 6, 2016·PloS One·Francisco Marco-JiménezJosé Salvador Vicente
May 23, 2016·Reproduction, Fertility, and Development·Jorge López-TelloPilar G Rebollar
Jun 19, 2018·Journal of Developmental Origins of Health and Disease·M BourdonG Jolivet
Jun 6, 2018·Reproduction : the Official Journal of the Society for the Study of Fertility·E CanonV Duranthon
Dec 27, 2017·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·Francesca M RussoKarel Allegaert

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