Rabies of canid biotype in wild dog (Lycaon pictus) and spotted hyaena (Crocuta crocuta) in Madikwe Game Reserve, South Africa in 2014-2015: Diagnosis, possible origins and implications for control

Journal of the South African Veterinary Association
Claude SabetaJune H Williams

Abstract

Both domestic and wild carnivore species are commonly diagnosed with rabies virus (RABV) infection in South Africa. Although the majority of confirmed rabies cases in wild carnivore species are reported from the yellow mongoose (Cynictis penicillata), the rest are from other wild carnivores including the highly endangered wild dog (Lycaon pictus). Lyssavirus infection was confirmed in two wild dogs and a spotted hyaena (Crocuta crocuta) in the Madikwe Game Reserve, North West province in South Africa, in 2014 and 2015, using a direct fluorescent antibody test and immunohistochemistry. There had been no new wild dog introductions to the Madikwe Game Reserve for many years and the wild dogs were last vaccinated against rabies approximately 11 years prior to the incident. The first euthanised wild dog was the last surviving of a break-away pack of 6, and the second was the last of a larger pack of 18, the rest of which died with no carcasses being found or carcasses too decomposed for sampling. Subsequent antigenic typing of the lyssaviruses indicated that they were canid RABVs. The RABVs originating from 22 wild carnivore species, 7 dogs, and a caprine, mostly from the North West province, were genetically characterised by target...Continue Reading

References

Jan 1, 1991·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·D M Haines, B J Chelack
Jul 1, 1993·Journal of Wildlife Diseases·S C GascoyneM Borner
Nov 22, 1995·Proceedings. Biological Sciences·P W KatL Munson
Jan 1, 1996·Journal of Wildlife Diseases·C Sillero-ZubiriD W Macdonald
Oct 1, 1996·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·P W KatL Munson
Dec 10, 1997·Journal of Wildlife Diseases·S CreelM J Appel
Jul 31, 1998·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·C J RhodesD W Macdonald
Dec 14, 2001·Proceedings of the National Academy of Sciences of the United States of America·M L EastC Pitra
Dec 25, 2002·Emerging Infectious Diseases·Daniel T HaydonM Karen Laurenson
Feb 8, 2003·Virus Research·C T SabetaL H Nel
Oct 19, 2005·Emerging Infectious Diseases·John Bingham
May 10, 2007·Molecular Biology and Evolution·Koichiro TamuraSudhir Kumar
May 29, 2007·Conservation Biology : the Journal of the Society for Conservation Biology·Sarah CleavelandCraig Packer
Nov 26, 2008·PLoS Neglected Tropical Diseases·Katie HampsonSarah Cleaveland
Mar 13, 2009·PLoS Biology·Katie HampsonAndy Dobson
Nov 11, 2009·Journal of Wildlife Diseases·Sonya Gowtage-SequeiraSarah Cleaveland
Dec 4, 2009·Clinical and Vaccine Immunology : CVI·Susanne ThalwitzerHans Lutz
Feb 27, 2010·PLoS Neglected Tropical Diseases·Tiziana LemboSarah Cleaveland
Mar 11, 2010·Virus Research·N Van ZylL H Nel
Dec 1, 2009·The Onderstepoort Journal of Veterinary Research·K T MoagaboJ M K Hyera
Aug 1, 2008·The Journal of Applied Ecology·Tiziana LemboSarah Cleaveland
Aug 29, 2012·PLoS Neglected Tropical Diseases·Meagan C FitzpatrickAlison P Galvani
Sep 26, 2012·The Journal of Animal Ecology·Michelle K MortersAndrew J K Conlan
Jun 29, 2013·Vector Borne and Zoonotic Diseases·Are R BerentsenCathleen A Hanlon
Jun 5, 2014·PloS One·Angela M DarnellMicaela Szykman Gunther
Jul 11, 2014·Journal of Virological Methods·Lorraine M McElhinneyAnthony R Fooks
Feb 17, 2015·The Onderstepoort Journal of Veterinary Research·Ernest NgoepeClaude Sabeta
May 29, 2015·Journal of the South African Veterinary Association·Wanda MarkotterLouis H Nel
Apr 16, 2016·Journal of Virological Methods·Jodie A JarvisApril D Davis
Aug 21, 2016·Vaccine·Claudio Sillero-ZubiriAnthony R Fooks

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Citations

Sep 24, 2021·Transboundary and Emerging Diseases·Reeta Subramaniam ManiSyam Chandran

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