Racial Differences in Treatment Decision-Making for Men with Clinically Localized Prostate Cancer: a Population-Based Study.

Journal of Racial and Ethnic Health Disparities
Jinping XuKendra Schwartz

Abstract

Racial differences in prostate cancer treatment patterns have motivated concerns about over- and undertreatment. We surveyed black and white patients with localized prostate cancer (LPC) regarding their treatment decision-making processes to gain a better perspective on factors associated with LPC treatment choice. We conducted a population-based, cross-sectional survey of 260 men (132 black, 128 white) aged ≤75 years, with newly diagnosed LPC. Our primary outcome was treatment choice (either surgery, radiation, or watchful waiting/active surveillance (WW/AS)), and our primary predictors were race and tumor risk level. Overall, treatment choice did not differ by race. As cancer risk increased, both black and white patients were more likely to undergo surgery and less likely to receive radiation. However, the pattern of WW/AS was different between white and black men. White men were less likely to select WW/AS as cancer risk increased, while risk level was unrelated to black men undergoing WW/AS. Urologist's recommendation had the greatest impact on men's treatment choice, followed by tumor risk level, age, and personal preferences. Although there were no overall racial differences in treatment choice, when stratified by tumor r...Continue Reading

References

Nov 22, 1995·JAMA : the Journal of the American Medical Association·S A OptenbergB Kramer
Jun 24, 2000·JAMA : the Journal of the American Medical Association·F J FowlerM J Barry
Nov 8, 2003·Onkologie·J Noldus, H Huland
Mar 11, 2004·Journal of General Internal Medicine·Vickie L ShaversAngela Fahey
Mar 17, 2004·The Journal of Urology·Willie UnderwoodJohn T Wei
Mar 30, 2005·Cancer·Thomas D DenbergJohn F Steiner
Oct 6, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Tracey L KrupskiMark S Litwin
May 19, 2007·The Journal of Urology·Ian ThompsonUNKNOWN AUA Prostate Cancer Clinical Guideline Update Panel
Jul 24, 2007·The Journal of Urology·Matthew R CooperbergPeter R Carroll
Jan 27, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Kelvin A MosesViraj A Master
Feb 4, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Matthew R CooperbergPeter R Carroll
Jun 18, 2010·BJU International·Daniel A Barocas, David F Penson
Apr 22, 2011·BJU International·B Joyce Davison, S Larry Goldenberg
Aug 13, 2011·Journal of the National Medical Association·Jinping XuKendra L Schwartz
Apr 18, 2012·Annals of Internal Medicine·Richard B Weinberg
Jul 20, 2012·The New England Journal of Medicine·Timothy J WiltUNKNOWN Prostate Cancer Intervention versus Observation Trial (PIVOT) Study Group
Nov 9, 2012·Journal of the American Board of Family Medicine : JABFM·Jinping XuKendra L Schwartz
Jul 6, 2013·Journal of Geriatric Oncology·Carolyn J PresleyCary P Gross

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Citations

Jul 18, 2018·Clinical Pediatrics·Vandra C HarrisEmily F Boss
Sep 12, 2019·Ciência & saúde coletiva·Raone Silva SacramentoEliana Zandonade
Sep 16, 2017·International Journal of Urology : Official Journal of the Japanese Urological Association·Alfredo Suarez-SarmientoBrian Shuch
Dec 17, 2016·Journal of the National Medical Association·Daniel M WalkerNina A Bickell

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