Racial discrepancies in the outcome of patients with hepatocellular carcinoma

Archives of Surgery
Lawrence E HarrisonMaria Korogodsky

Abstract

There is a marked variation in the outcome of patients with hepatocellular carcinoma with respect to race and ethnicity. Rates among African American and Hispanic individuals are elevated as compared with those among white individuals. Retrospective review of a prospective database. Demographic information, clinical staging, and other defining factors, including the absence or presence of hepatitis, cirrhosis, and alcohol abuse, were analyzed by patient interviews and review of the medical record. Urban tertiary referral teaching hospital. Patients diagnosed as having hepatocellular carcinoma between July 1997 and June 2003 (N = 264). Main Outcome Measure Overall survival rates. Based on multivariate analysis, race was identified as an independent predictor of survival. While there was no difference in the distribution of patient or tumor characteristics between the 2 groups, African American/Hispanic patients had a 5-year survival rate of 12%, which was significantly lower than that of white patients (50%; P = .001). This study demonstrates a significant discrepancy in overall survival of African American/Hispanic patients as compared with that of white patients. The reason for this difference cannot be explained by patient or...Continue Reading

Citations

Jan 1, 2010·International Journal of Surgical Oncology·Jue Wang, Fen Wei Wang
Jan 25, 2012·The Surgical Clinics of North America·Heena P Santry, Sherry M Wren
Mar 7, 2006·Primary Care·Victor Alejandro Diaz
Oct 16, 2007·Digestive Diseases and Sciences·Nyingi Kemmer, Guy W Neff

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