Racial inequity in methadone dose at delivery in pregnant women with opioid use disorder.

Journal of Substance Abuse Treatment
Emily W RosenthalDennis J Hand

Abstract

Medications for opioid use disorder, including methadone, combined with comprehensive wraparound services, are the gold standard for treatment in pregnancy. Higher methadone doses are associated with treatment retention in pregnancy and relapse prevention. Given known inequities where individuals of color tend to be prescribed lower doses of opioids for other conditions, the purpose of this study was to determine whether there is racial inequity in methadone dose at delivery in pregnant women with opioid use disorder. Retrospective review of medical charts identified pregnant women (N = 339) treated with methadone for opioid use disorder during pregnancy at one center from 2012 to 2017. Variables extracted from medical records included race, demographic and relevant clinical information (e.g., methadone dose at delivery, height, weight, etc.). Analyses used simple and multiple linear regressions to determine associations between these characteristics and methadone dose at delivery. The mean methadone doses at delivery among women of color and white women were 105.8 mg and 144.9 mg, respectively (p < .0001). After adjusting for maternal age, gestational age at delivery, body mass index, type of opioid used, and parity, race was ...Continue Reading

References

Apr 21, 1998·Obstetrics and Gynecology Clinics of North America·K KaltenbachL Finnegan
Mar 23, 1999·JAMA : the Journal of the American Medical Association·E C StrainM L Stitzer
Dec 1, 2001·The American Journal of Psychiatry·K WellsC Sherbourne
Sep 17, 2003·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Carmen R GreenApril H Vallerand
Jan 17, 2004·Drug and Alcohol Dependence·Bruna BrandsUsoa Busto
Dec 26, 2006·Journal of Palliative Medicine·Alexie Cintron, R Sean Morrison
Jul 12, 2011·Journal of Substance Abuse Treatment·Brittany AlbrightWilliam Rayburn
Jan 29, 2016·Journal of Substance Abuse Treatment·Jeremy Mennis, Gerald J Stahler
Apr 5, 2016·Proceedings of the National Academy of Sciences of the United States of America·Kelly M HoffmanM Norman Oliver
Dec 28, 2017·Maternal and Child Health Journal·Natasha ParekhDavid Kelley
Mar 13, 2018·Obstetrics and Gynecology·Amirhossein MoaddabSteven L Clark
Aug 10, 2018·MMWR. Morbidity and Mortality Weekly Report·Sarah C HaightWilliam M Callaghan
Nov 26, 2019·Obstetrics and Gynecology·Jasmine D JohnsonAlison M Stuebe

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Australian Family Physician
John Sherman
The Western Journal of Medicine
I B Anderson, T E Kearney
The Medical Journal of Australia
D S Bell
© 2021 Meta ULC. All rights reserved