Racial/Ethnic differences in the prevalence and incidence of Metabolic Syndrome in high-income countries: a protocol for a systematic review

Nicholas Kofi AdjeiHajo Zeeb


Background: Metabolic Syndrome is a constellation of various cardiovascular and type 2 diabetes risk factors, such as abdominal obesity, atherogenic dyslipidemia, high blood pressure and high blood glucose, but its prevalence varies widely by geographical region, sex and race/ethnicity. The objective of this study will be to examine the prevalence and incidence of metabolic syndrome among adults of different racial/ethnic origins in high-income countries. Methods: We designed and registered a study protocol for a systematic review of descriptive epidemiological data. Observational studies (e.g. cross-sectional and cohort studies) reporting morbidity data of metabolic syndrome and conducted in a wide range of adult people (e.g. different racial/ethnic origins, including migrants) will be included. The primary outcome will be the prevalence and incidence of metabolic syndrome. Secondary outcomes will be the prevalence and incidence of individual components of metabolic syndrome (e.g. abdominal obesity, dyslipidemia, high blood pressure and high blood glucose). Literature searches will be conducted in several electronic databases (from inception onwards), including MEDLINE, Web of Science Core Collection (Science Citation Index an...Continue Reading

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