Radiation dose constraints for organs at risk in neuro-oncology; the European Particle Therapy Network consensus

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
Maarten Lambrechtwork package 1 of the taskforce “European Particle Therapy Network” of ESTRO

Abstract

For unbiased comparison of different radiation modalities and techniques, consensus on delineation of radiation sensitive organs at risk (OARs) and on their dose constraints is warranted. Following the publication of a digital, online atlas for OAR delineation in neuro-oncology by the same group, we assessed the brain OAR-dose constraints in a follow-up study. We performed a comprehensive search to identify the current papers on OAR dose constraints for normofractionated photon and particle therapy in PubMed, Ovid Medline, Cochrane Library, Embase and Web of Science. Moreover, the included articles' reference lists were cross-checked for potential studies that met the inclusion criteria. Consensus was reached among 20 radiation oncology experts in the field of neuro-oncology. For the OARs published in the neuro-oncology literature, we summarized the available literature and recommended dose constraints associated with certain levels of normal tissue complication probability (NTCP) according to the recent ICRU recommendations. For those OARs with lacking or insufficient NTCP data, a proposal for effective and efficient data collection is given. The use of the European Particle Therapy Network-consensus OAR dose constraints summa...Continue Reading

Citations

Jul 30, 2019·The British Journal of Radiology·Hakan NystromPetra Witt Nystrom
Mar 31, 2020·Molecular Oncology·Cai GrauDamien C Weber
May 9, 2019·The British Journal of Radiology·Damien C WeberAlessia Pica
Feb 6, 2021·Radiation Oncology·Guillaume VoginLoic Feuvret
Dec 10, 2020·Journal of medical and biological engineering·Patricia ClementEsther A H Warnert
Dec 15, 2020·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Stephanie E CombsGiuseppe Minniti
Jul 31, 2019·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·A BeddokUNKNOWN Gortec et de trois centres français
Apr 6, 2021·Pediatric Blood & Cancer·Samir PatelAnita Mahajan
Apr 20, 2021·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Almut DutzSteffen Löck
May 21, 2021·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Daniëlle B P EekersEsther G C Troost
Jul 22, 2021·International Journal of Particle Therapy·Piero FossatiEugen B Hug
Jul 10, 2021·Critical Reviews in Oncology/hematology·Mikaela Dell'OroEva Bezak
Aug 31, 2021·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Magdalena GarbaczAntoni Rucinski
Apr 8, 2020·Neuroendocrinology·Anna SundlövOla Lindgren
Sep 21, 2021·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Kimberley S KoetsierHelen A Shih
Dec 3, 2021·Journal of Magnetic Resonance Imaging : JMRI·Jin LiuHai Li

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.