PMID: 8971963Dec 1, 1996Paper

Radiation dose distributions in three dimensions from tomographic optical density scanning of polymer gels: I. Development of an optical scanner

Physics in Medicine and Biology
J C GoreR J Schulz

Abstract

A new method of dosimetry of ionizing radiations has been developed that makes use of tissue-equivalent polymer gels which are capable of recording three-dimensional dose distributions. The dosimetric data stored within the gels are measured using optical tomographic densitometry. The dose-response mechanism relies on the production of light scattering microparticles which result from the polymerization of acrylic comonomers dispersed in the gel. The attenuation of a collimated light beam caused by scattering in the irradiated optically turbid medium is directly related to the radiation dose over the range 0-10 Gy. An optical scanner has been developed which incorporates an He-Ne laser, photodiode detectors, and a rotating gel platform. Using mirrors mounted on a translating stage, the laser beam scans across the gel between each incremental rotation of the platform. Using the set of optical density projections obtained, a cross sectional image of the radiation field is then reconstructed. Doses in the range 0-10 Gy can be measured to better than 5% accuracy with a spatial resolution approximately 2 mm using the current prototype scanner. This method can be used for the determination of three-dimensional dose distributions in i...Continue Reading

References

Nov 1, 1978·Physics in Medicine and Biology·J C Gore, P S Tofts
Sep 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·G N Ramachandran, A V Lakshminarayanan
Jan 1, 1980·Physics in Medicine and Biology·P S Tofts, J C Gore
May 1, 1996·Medical Physics·M J MaryanskiJ C Gore
Sep 1, 1994·Physics in Medicine and Biology·M J MaryanskiJ C Gore

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Citations

Apr 16, 1998·International Journal of Radiation Oncology, Biology, Physics·D A LowJ A Purdy
Oct 23, 1998·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·D M Duggan, C W Coffey
Nov 27, 2008·Physics in Medicine and Biology·Heather M WhitneyJohn C Gore
Feb 13, 2010·Physics in Medicine and Biology·C BaldockL J Schreiner
May 17, 2011·Physics in Medicine and Biology·Andrew ThomasMark Oldham
Jul 2, 2011·Physics in Medicine and Biology·Andrew ThomasMark Oldham
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Aug 30, 2003·Medical Physics·Y XuaMarek J Maryanski
Jun 12, 2004·Medical Physics·Mark Oldham, Leonard Kim
Dec 10, 1999·Medical Physics·J G WolodzkoA Appleby
Jan 10, 2013·Medical Physics·Adam K GlaserDavid J Gladstone
May 3, 2013·Medical Physics·Leith Rankine, Mark Oldham
Oct 5, 2013·Medical Physics·Mathieu GouletLuc Gingras
Nov 9, 2006·Medical Physics·Pengyi GuoMark Oldham
Jun 10, 2010·Medical Physics·O A ZeidanM J Maryanski
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Feb 26, 2008·Medical Physics·Michelle Hilts, Andrew Jirasek
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Mar 9, 2007·Journal of Biomedical Optics·Mark OldhamMark Dewhirst

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