Radiation dose to the internal pudendal arteries from permanent-seed prostate brachytherapy as determined by time-of-flight MR angiography

International Journal of Radiation Oncology, Biology, Physics
Caitlin GillanJuanita Crook

Abstract

To determine the feasibility of time-of-flight magnetic resonance (MR) angiography to visualize the internal pudendal arteries (IPAs) in potent men undergoing permanent-seed prostate brachytherapy and to calculate the radiation dose received by these arteries. Prostate brachytherapy is performed at the University Health Network/Princess Margaret Hospital by use of transrectal ultrasound (TRUS) preplanning and preloaded needles. All patients received (125)I, with a mean seed activity of 0.32 mCi/seed (0.41 U). Postplan evaluation is performed at 1 month by magnetic resonance-computed tomography fusion. Twenty consecutive potent men had time-of-flight MR angiography as part of their postplan evaluation. The mean V100 was 96.5%, and the mean D90 was171.5 Gy. The IPAs were easily visualized for 18 of the 20 men. The mean peak dose received by the IPA was 17 Gy. The highest peak dose received by any patient was 38.2 Gy, with only 1 other patient receiving a peak dose greater than 30 Gy. Eleven of 18 had a measurable portion of at least 1 IPA that received 10% of the prescribed dose (V10 = 14.5 Gy). Only 2 patients had nonzero values for V25. The distal third of the IPA received the highest dose for 16 of the 18 patients. The IPAs ca...Continue Reading

References

Jun 1, 1985·International Journal of Radiation Oncology, Biology, Physics·B Mittal
Jan 9, 1998·International Journal of Radiation Oncology, Biology, Physics·M J Zelefsky, J F Eid
Apr 16, 1998·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·A H FriedlanderP M Lambert
Mar 22, 2000·International Journal of Radiation Oncology, Biology, Physics·S J DiBiaseS Sutlief
Nov 10, 2000·International Journal of Radiation Oncology, Biology, Physics·G S MerrickJ G Donzella
Jun 8, 2001·International Journal of Radiation Oncology, Biology, Physics·G S MerrickM L Benson
Feb 19, 2002·International Journal of Radiation Oncology, Biology, Physics·Luca IncrocciPeter C Levendag
Jul 6, 2004·International Journal of Radiation Oncology, Biology, Physics·Ugur SelekDeborah Kuban
Jul 28, 2004·International Journal of Radiation Oncology, Biology, Physics·Mark K BuyyounouskiAlan Pollack
Jan 5, 2005·International Journal of Radiation Oncology, Biology, Physics·Patrick W McLaughlinMarc Kessler
May 14, 2005·International Journal of Radiation Oncology, Biology, Physics·Gregory S MerrickZachariah A Allen

❮ Previous
Next ❯

Citations

Feb 4, 2012·International Journal of Radiation Oncology, Biology, Physics·J Taylor WhaleySteven J Frank
Jan 24, 2012·Brachytherapy·Brian J DavisUNKNOWN American Brachytherapy Society
Apr 26, 2011·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·J Crook
Aug 21, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Gerard J van der WielenLuca Incrocci
Jul 1, 2017·Nature Reviews. Urology·Nicholas G ZaorskyEric M Horwitz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
Gerard J van der WielenLuca Incrocci
JAMA : the Journal of the American Medical Association
I GoldsteinR J Krane
© 2022 Meta ULC. All rights reserved