Radiation exposure during TACE procedures using additional cone-beam CT (CBCT) for guidance: safety and precautions

Acta Radiologica
M JonczykG Gebauer

Abstract

Background During transarterial chemoembolization (TACE), cone-beam computed tomography (CBCT) can be used for tumor and feeding vessel detection as well as postembolization CT imaging. However, there will be additional radiation exposure from CBCT. Purpose To evaluate the additional dose raised through CBCT-assisted guidance in comparison to TACE procedures guided with pulsed digital subtraction angiography (DSA) alone. Material and Methods In 70 of 140 consecutive patients undergoing TACE for liver cancer, CBCT was used to facilitate the TACE. Cumulative dose area product (DAP), cumulative kerma(air), DAP values of DSA, total and cine specific fluoroscopy times (FT) of 1375 DSA runs, and DAP of 91 CBCTs were recorded and analyzed using Spearman's correlation, Mann-Whitney U-test, and Kruskal-Wallis test. P values < 0.05 were considered significant. Results Additional CBCT increased DAP by 2% ( P = 0.737), kerma(air) by 24.6% ( P = 0.206), and FT by 0.02% ( P = 0.453). Subgroup analysis revealed that postembolization CBCT for detection of ethiodized oil deposits added more DAP to the procedure. Performing CBCT-assisted TACE, DSA until first CBCT contributed about 38% to the total DAP. Guidance CBCT acquisitions conduced to 6% ...Continue Reading

References

May 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·L MondazziG Idèo
Feb 8, 2006·Radiation Protection Dosimetry·F W Schultz, J Zoetelief
Jun 28, 2006·Cardiovascular and Interventional Radiology·Nico HidajatRalf Jürgen Schröder
Aug 31, 2011·Journal of Vascular and Interventional Radiology : JVIR·Nishita KotharyLawrence V Hofmann
Sep 11, 2012·European Journal of Radiology·Jin IwazawaTakashi Mitani
Oct 8, 2013·Journal of Vascular and Interventional Radiology : JVIR·Rongxin ChenMingDe Lin
Aug 6, 2014·Nature Reviews. Clinical Oncology·Alejandro FornerJean-Luc Raoul
Aug 26, 2014·Cardiovascular and Interventional Radiology·Christian Scheurig-MuenklerThomas J Kroencke
Dec 6, 2014·Cardiovascular and Interventional Radiology·Ruediger Egbert SchernthanerJean-François Geschwind
Jan 28, 2015·Radiology·Vania TacherJean-François Geschwind
Jul 17, 2015·Cardiovascular and Interventional Radiology·Blanche BapstMaxime Ronot
Oct 22, 2015·Digestive Diseases·Yasunori MinamiMasatoshi Kudo
Dec 23, 2016·Cardiovascular and Interventional Radiology·Shamar YoungJafar Golzarian

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Citations

Jun 22, 2019·Cardiovascular and Interventional Radiology·Lauranne PironBoris Guiu
Mar 23, 2019·Acta Radiologica·Ulrich GrosseRüdiger Hoffmann
Apr 8, 2021·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Jean IzaaryeneMarjorie Ferre

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