PMID: 1200570Nov 1, 1975Paper

Radiation failures in cancer of the larynx

The Annals of Otology, Rhinology, and Laryngology
E M SkolnikM A Wheatley

Abstract

Overwhelming statistics have been published regarding the success of radiation therapy in the management of laryngeal carcinoma. The fate of those patients whose cancers are not controlled by radiotherapy is often left to speculation. An analysis is made of 61 patients with early and advanced laryngeal cancer treated initially with radiation therapy and subsequently operated upon because of recurrent or persistent tumor. Frequently, diagnosis of recurrence is difficult or delayed. Preservation of voice can only be accomplished when recurrence of T1 and T2 lesions is detected early and strict criteria are followed. Conservation surgery is not feasible for early lesions which progress after radiation failure. Advanced T2 and T4 lesions which become radiation failures also require laryngectomy for salvage. In cancer of the larynx, there is a definite, identifiable group of patients in whom surgery would be advisable as the initial therapy.

References

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Citations

Apr 1, 1996·The Laryngoscope·O LaccourreyeD Brasnu
Sep 1, 1988·International Journal of Radiation Oncology, Biology, Physics·C H TerhaardL A Ravasz
Oct 1, 1991·American Journal of Surgery·R S Lavey, T C Calcaterra
Dec 1, 1992·American Journal of Surgery·J J ManniG J Hordijk
Aug 4, 2015·Otolaryngologic Clinics of North America·Michelle Mizhi ChenOllivier Laccourreye
Apr 1, 1983·The Journal of Laryngology and Otology·K H LamG B Ong
Mar 1, 1991·The Annals of Otology, Rhinology, and Laryngology·R D Nichols, S A Mickelson
Feb 26, 2003·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·John YiotakisGeorge Adamopoulos
Feb 1, 1979·Clinical Otolaryngology and Allied Sciences·J Lundgren, J Olofsson
Jul 1, 1980·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·J R JacobsJ H Ogura

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