PMID: 9545116Apr 17, 1998Paper

Radiation-induced painless thyrotoxic thyroiditis followed by hypothyroidism: a case report and literature review

Thyroid : Official Journal of the American Thyroid Association
T AizawaK Hashizume

Abstract

A 68-year-old woman presented with a small painless goiter and thyrotoxic symptoms immediately after 50-Gy external radiation for mucoepidermoid carcinoma of the submandibular gland. Elevated serum thyroid hormone and thyroglobulin levels, and undetectable serum thyrotropin level, together with extremely low thyroidal radioiodine uptake established the diagnosis of painless thyrotoxic thyroiditis. Thyroidal autoantibodies were negative. At follow-up without medication, all the symptoms disappeared, and laboratory abnormalities normalized within 6 months. One year later, the patient developed compensated hypothyroidism as indicated by elevated serum thyrotropin level with low normal serum thyroid hormone levels.

References

Sep 1, 1985·Archives of Internal Medicine·J B BlitzerC T Chung
Feb 1, 1983·The American Journal of Medicine·M M KaplanM J Sack

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Citations

Aug 4, 2001·Thyroid : Official Journal of the American Thyroid Association·G H Daniels
Nov 24, 1999·Thyroid : Official Journal of the American Thyroid Association·F AlagölF Dizdaroglu
Mar 10, 2011·Thyroid : Official Journal of the American Thyroid Association·Laura Calvi, Gilbert H Daniels
Feb 4, 2012·Thyroid : Official Journal of the American Thyroid Association·Ming-Kai ChenDavid W Cheng
Jun 1, 2000·Radiology·S GrippR Willers
Mar 31, 2010·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Rachel P Espiritu, Diana S Dean

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