Jul 1, 1976

Radiation-induced xerostomia in cancer patients. Effect on salivary and serum electrolytes

Cancer
S DreizenB M Levy

Abstract

Saliva and serum electrolyte concentrations were monitored in 30 patients given a course of xerostomia-producing cancer radiotherapy. The mean flow rate of stimulated whole saliva decreased 83.3% during a 6-week treatment period. The striking reduction in saliva output was accompanied by significant increases in saliva Na+, Cl-, Ca++, Mg++ and Prot.- concentrations and by a decrease in saliva HCO3- content. The xerostomic saliva was more concentrated and had a greater salinity than the pretreatment saliva in each instance. In contrast, none of the serum electrolytes measured was significantly altered by the subtotal salivary shutdown.

  • References5
  • Citations113

References

  • References5
  • Citations113

Citations

Mentioned in this Paper

Chloride Ion Level
Electrolytes
Calcium
Potassium
Effects of Radiation
Carbonic Acid Ions
Radiotherapy, Targeted
Sodium
Saliva
Malignant Neoplasms

About this Paper

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