PMID: 8949719Aug 1, 1996Paper

Radiation related complications after ruthenium plaque radiotherapy of uveal melanoma

The British Journal of Ophthalmology
P SummanenA Tarkkanen

Abstract

To analyse radiation related complications and secondary enucleation after irradiation of malignant uveal melanoma with ruthenium-106 plaques. A series of 100 consecutive eyes irradiated in 1981-91 was analysed using the life table method and the Cox proportional hazards model. The median apical and scleral tumour dose was 100 Gy (range 15-200 Gy) and 1000 Gy (range 200-1200 Gy), respectively. The median follow up time was 2.8 and 2.0 years (range 1 month to 10 years) for anterior and posterior segment complications, respectively. The 3 and 5 year probabilities of being without radiation cataract were 73% and 63%, without neovascular glaucoma 91% and 81%, without vitreous haemorrhage 83% and 74%, without radiation maculopathy 85% and 70%, and without radiation optic neuropathy 90% and 88%, respectively. The risk of radiation cataract was highest with large tumour size (T1 + T2 v T3, p = 0.0027; height < or = 5 v > 5 mm, p = 0.029; largest basal diameter (LBD) < or = 15 v > 15 mm, p < 0.0001) and location of anterior tumour margin anterior v posterior to the equator (p = 0.0003); the risk of neovascular glaucoma with large size (T1 + T2 v T3, p = 0.039; LBD < or = 15 mm v 15 mm, p = 0.021); and the risk of maculopathy and optic ...Continue Reading

References

Aug 1, 1992·Ophthalmology·D R GuyerE S Gragoudas
Aug 1, 1990·International Journal of Radiation Oncology, Biology, Physics·M DeckerD Ahn
Sep 1, 1990·International Journal of Radiation Oncology, Biology, Physics·D LinstadtT L Phillips
Feb 1, 1990·Archives of Ophthalmology·D H CharR D Stone
Feb 1, 1985·Ophthalmology·E S GragoudasA Koehler
Jan 1, 1986·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·M H FoersterG Meyer-Schwickerath
Nov 1, 1986·The British Journal of Ophthalmology·P K Lommatzsch
May 1, 1985·Archives of Ophthalmology·D Seigel
Apr 1, 1970·The British Journal of Ophthalmology·P A Macfaul, M A Bedford
Mar 1, 1966·The British Journal of Ophthalmology·H B Stallard
Jun 1, 1982·Archives of Ophthalmology·D H Char, J R Castro
Dec 1, 1982·Ophthalmology·G C BrownN J Schatz
Dec 1, 1982·Ophthalmology·G C BrownN J Schatz
Aug 1, 1994·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·P K LommatzschF Rohrwacher
Sep 1, 1993·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·J J AugsburgerD Mullen
Aug 1, 1993·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M KleineidamS M Bentzen
Jul 15, 1993·International Journal of Radiation Oncology, Biology, Physics·J M QuiveyS M Kroll
Jul 15, 1993·International Journal of Radiation Oncology, Biology, Physics·M KleineidamL W Brady

❮ Previous
Next ❯

Citations

Nov 24, 2006·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·L M HeindlH L J Knorr
Feb 23, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Andrea RussoBertil Damato
May 26, 2005·International Journal of Radiation Oncology, Biology, Physics·Bertil DamatoR Douglas Errington
Mar 5, 2005·Ophthalmology·Efstathios T DetorakisBradley R Straatsma
Nov 12, 2003·Survey of Ophthalmology·Flavio A Marigo, Paul T Finger
Feb 26, 2000·Ophthalmology·L A LevinS Lessell
May 9, 2000·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M ZehetmayerR Pötter
Feb 9, 2000·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·R E Tjho-HeslingaJ W Leer
Apr 17, 2002·International Journal of Radiation Oncology, Biology, Physics·Robert Michael HermannClemens F Hess
Jun 8, 2002·Progress in Retinal and Eye Research·J G Journée-de Korver, J E E Keunen
Mar 1, 2012·Retina·Carlos BianciottoJerry A Shields
Sep 20, 2005·The British Journal of Ophthalmology·R van GinderdeurenW Spileers
Aug 12, 2009·Clinical Ophthalmology·Chryssanthi KoutsandreaMichael Apostolopoulos
Jul 2, 2003·Drugs & Aging·Kaykhosrov Manuchehri, Graham Kirkby
Jun 29, 2011·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Hatem KremaRand Simpson
Jul 10, 2010·International Journal of Radiation Oncology, Biology, Physics·Paul T FingerUNKNOWN Palladium-103 for Choroidal Melanoma Study Group
Apr 27, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Karijn M S VerschuerenCorrie A M Marijnen
Jan 19, 2010·Ophthalmology·Carlos BianciottoJerry A Shields
Jan 28, 2009·Survey of Ophthalmology·Nathan M Radcliffe, Paul T Finger
Jun 26, 2007·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Emma DawsonJohn Lee
Jan 27, 2009·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Sohel SomaniE Rand Simpson
Apr 20, 2004·International Journal of Radiation Oncology, Biology, Physics·Khaled EmaraE Rand Simpson
May 10, 2006·International Journal of Radiation Oncology, Biology, Physics·Andreas O SchuelerWolfgang Sauerwein
Jul 2, 2005·International Journal of Radiation Oncology, Biology, Physics·Bertil DamatoR Douglas Errington
Jun 9, 2004·American Journal of Ophthalmology·L KodjikianJ D Grange
Jun 5, 2012·International Journal of Radiation Oncology, Biology, Physics·Niloufer KhanArun D Singh
Aug 26, 2011·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Karin MullerGré P M Luyten
Apr 27, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ira SeibelAntonia M Joussen
Feb 27, 2008·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Gloria Amparo Flórez-MorenoSergio Iván Tobón-Arroyave
Mar 28, 2006·American Journal of Ophthalmology·Daniel J WeisbrodE Rand Simpson
Oct 16, 2016·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Marina MarinkovicCarien L Creutzberg
Apr 20, 2017·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Tae Wan KimSung Ho Moon
Dec 2, 2014·International Ophthalmology Clinics·Hassan A Aziz, Arun D Singh

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Related Papers

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
P K LommatzschF Rohrwacher
Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
P K LommatzschE Schuster
© 2021 Meta ULC. All rights reserved