Radiation response modified by degradable starch microspheres. Experiments on the rat's foot

Acta Radiologica: Oncology, Radiation, Physics, Biology
J O ForsbergB Larsson

Abstract

Skin reaction in the rat's foot was used as an experimental method to evaluate the protective potential of profound temporary hypoxia against roentgen radiation produced by a linear accelerator. Hypoxia was induced by intraarterial injection of degradable starch microspheres. The irradiation dose needed to evoke a certain reaction in the hypoxic feet was 2.0 times the dose giving the same reaction in a control group. The results point towards a new technique of inducing local hypoxia in healthy tissues which need to be protected in an irradiation field.

References

Jan 1, 1978·Acta Radiologica: Oncology, Radiation, Physics, Biology·J O Forsberg, B Jung
Jan 1, 1978·Acta Radiologica: Oncology, Radiation, Physics, Biology·J O ForsbergB Larsson
Apr 1, 1972·The British Journal of Radiology·J F FowlerK Butler

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Citations

Jan 1, 1989·Life Sciences·P K Gupta, C T Hung
Jan 1, 1987·Acta Oncologica·P KäleboI Turesson
Jan 1, 1978·Acta Radiologica: Oncology, Radiation, Physics, Biology·J O ForsbergB Larsson

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