Abstract
Between 1976 and 1992, 32 patients aged 75 and older with stage I-II non-small cell lung cancer (NSCLC) were given definitive radiation therapy. These patients did not undergo surgery because of old age, poor cardiac/pulmonary condition, or refusal to give consent. The mean age was 79 years, and 11 patients were over 80 years old. The histologic type was squamous cell carcinoma in 25 patients and adenocarcinoma in 7. The clinical T and N stage was T1N0 in 4 patients, T2N0 in 9, and T2N1 in 19. The total dose of radiation therapy given to each patient exceeded 60 Gy using 10-MV X-rays. The treatment was completed in all 32 patients without treatment-related complications. The 2- and 5-year overall actuarial survival rates wer 40% and 16%, respectively. Eleven intercurrent deaths occurred, including 7 patients who died of heart disease. The 2- and 5-year cause-specific survival rates were 57% and 36% respectively. None of the patients developed severe pneumonitis requiring hospitalization. All but three patients received radiation therapy on an inpatient basis. The mean duration of the hospital stay for initial treatment was 56 days, and mean ratio to total survival period (mean 739 days) was 8%. Although many elderly patients ha...Continue Reading
Citations
Feb 10, 2004·Gynecologic Oncology·Hideyuki SakuraiTakashi Nakano
Apr 3, 2001·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·K HayakawaH Niibe
Aug 17, 2002·International Journal of Radiation Oncology, Biology, Physics·Branislav JeremicMichael Bamberg
Sep 25, 2002·Critical Reviews in Oncology/hematology·Riccardo A Audisio, Andrew P Zbar
Jul 20, 2001·Thorax·N P Rowell, C J Williams
Aug 6, 2013·Pathology Oncology Research : POR·Milan VosmikJiri Petera
Jun 3, 1999·Radiology·N MitsuhashiH Niibe
Sep 16, 2005·Chest·Juan P WisniveskyThomas McGinn
Sep 15, 2004·Chest·Jeffrey L PortNasser K Altorki
Jan 19, 2010·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Neil BaymanCorinne Faivre-Finn
May 6, 2008·Anesthesiology Clinics·Paul M Heerdt, Bernard J Park
Jan 14, 2010·Thoracic Surgery Clinics·Paul M Heerdt, Bernard J Park
May 10, 2006·International Journal of Radiation Oncology, Biology, Physics·Branislav JeremićSlobodan Milisavljević
Mar 7, 2006·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Sol San JoséFerran Guedea
Feb 19, 2000·Hematology/oncology Clinics of North America·B Zachariah, L Balducci
Oct 6, 2014·Archivos de bronconeumología·María RodríguezGonzalo Varela
Aug 22, 2006·Radiation Oncology·Peter FritzErich Stoelben
Sep 30, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Branislav JeremićSlobodan Milisavljević
Sep 26, 2003·Seminars in Surgical Oncology·Frank B ZimmermannBranislav Jeremic
Jan 11, 2007·Current Opinion in Anaesthesiology·Maria D Castillo, Paul M Heerdt
Jan 6, 2006·The Cancer Journal·Loren K Mell, Arno J Mundt
Mar 11, 2015·The Cochrane Database of Systematic Reviews·Nick P Rowell, Chris Williams