Radical Fragment Coupling Route to Geminal Bis(boronates)

Organic Letters
Qi Huang, Samir Z Zard

Abstract

The radical addition of dithiocarbonates to 1,1-bis(boronyl)-3-butene and related alkenes occurs without complications from fragmentation or hydrogen atom abstraction and delivers a vast array of highly functional geminal bis(boronates). The ability to assemble geminal bis(boronates) bearing polar functional groups not readily obtained through existing methods is particularly noteworthy. This approach also opens up access to geminal bis(boronyl) cyclopropanes and geminal bis(boronyl) tetrahydroquinolines.

References

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Citations

Dec 6, 2019·Chemical Communications : Chem Comm·Nivesh KumarAhmad Masarwa
Mar 7, 2020·Chemistry : a European Journal·Ahmad MasarwaAlexander Shames
Sep 1, 2020·Angewandte Chemie·Valerio FasanoVarinder K Aggarwal

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