Radical prostatectomy: anatomical predictors of success or failure

The Journal of Urology
D F PaulsonE B Cox

Abstract

A total of 143 patients underwent radical prostatectomy. Surgical specimens were evaluated with respect to local extent of disease, Gleason grade of the primary and relative nuclear roundness of the surgical specimen. The probability of disease control in the total population was 88 per cent at 5 years. Only 8 per cent of the patients who had disease confined to the specimen failed compared to 14 per cent of those who demonstrated extension outside of the surgical margins. The incidence of failure increased as a function of seminal vesicle involvement. Seminal vesicle involvement was greatest among patients with a Gleason grade greater than 7. Postoperative radiation did not offer any apparent advantage in patients with positive margins.

References

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Apr 1, 1980·Cancer·Patrick C Walsh, Hugh J Jewett

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Citations

Jul 1, 1992·The Journal of Urology·H G van der PoelJ A Schalken
Mar 1, 1995·International Journal of Urology : Official Journal of the Japanese Urological Association·W P WitjesF M Debruyne
Dec 1, 1995·The Prostate·W P WitjesF M Debruyne
Jun 1, 1994·Annals of Medicine·J O Salo, S Rannikko
Apr 18, 2009·Current Urology Reports·Stephen M Graham, Jeffrey M Holzbeierlein
Oct 8, 2008·Annals of the New York Academy of Sciences·Fayez T Hammad
Mar 1, 1992·The Journal of Urology·T J KennedyR H Troup
Nov 1, 1993·British Journal of Urology·M OhoriP T Scardino
Jan 1, 1993·Scandinavian Journal of Urology and Nephrology·K V Pedersen, A Herder
Aug 2, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·L ChengD G Bostwick
Sep 1, 1991·International Journal of Radiation Oncology, Biology, Physics·Z PetrovichD G Skinner

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