PMID: 7538694Jan 1, 1995Paper

Radical prostatectomy or deferred treatment?

Seminars in Surgical Oncology
U E Studer

Abstract

Screening for prostate cancer has intensified, due both to increased patient and physician awareness and to the availability of new, more sensitive diagnostic tools (prostate-specific antigen [PSA], rectal ultrasound, etc.). Consequently, the number of newly diagnosed cases of prostatic cancer is rising rapidly, whereas the frequency of death due to prostate cancer remains almost stable. It must therefore be assumed that the number of patients in whom a diagnosed prostate cancer will not be fatal is also increasing. Consequently, not every prostatic carcinoma requires radical treatment when diagnosed. Also, it must be concluded that not every man who is a long-term survivor after radical prostatectomy owes his survival to the treatment. Long-term survival may reflect the relatively benign biological potential of this disease in an individual patient. Therefore there is an inherent risk of overtreating patients and this must be weighed against the costs, the postoperative morbidity, and the mortality, albeit low, of a radical prostatectomy. Nevertheless, as long as we do not have diagnostic tools which, at an early stage of prostatic cancer, enable us to determine whether a carcinoma will ultimately have a fatal outcome, we are ...Continue Reading

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Citations

Dec 10, 1997·International Journal of Radiation Oncology, Biology, Physics·R R AllisonR Huben
Feb 20, 1999·American Journal of Clinical Oncology·R PazdurH A Burris
Nov 12, 2010·The Cochrane Database of Systematic Reviews·Josephine HegartyMeredith Wallace Kazer

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