PMID: 2511445Dec 1, 1989Paper

Radio-adaptive response: characterization of a cytogenetic repair induced by low-level ionizing radiation in cultured Chinese hamster cells

Mutation Research
T Ikushima

Abstract

Pretreatment with low doses of beta-rays from incorporated tritiated thymidine ([3H]dThd) or of Co-60 gamma-rays (1 or 5 cGy) rendered actively growing Chinese hamster V79 cells more resistant to the induction of micronuclei or sister-chromatid exchanges (SCEs) by a subsequent high dose of gamma-rays (1 Gy). This adaptive response to ionizing radiation (radio-adaptive response) can be induced by an optimal range of low doses of 3H beta-rays, but not by much lower or higher adapting doses. Full expression of the adaptive response induced by the exposure to low doses of 60Co gamma-rays occurred 4 h after the adapting dose. The cells pre-exposed to low doses of gamma-rays showed cross-resistance to challenge doses of gamma-rays themselves and also of mitomycin C (MMC) and near ultraviolet light (UV-B, 313 nm), but not to those of ethyl methanesulfonate (EMS) or cis-platinum (II) diammine dichloride (cisplatin) for SCE induction. These results suggest that the radio-adaptive response mechanistically couples to the repair network which copes with chromatin lesions induced by MMC and UV-B.

References

Jan 1, 1988·Annual Review of Biochemistry·T LindahlY Nakabeppu
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Citations

Nov 26, 2002·International Journal of Cancer. Journal International Du Cancer·Octávia Monteiro GilJosé Rueff
Jun 1, 1993·Mutation Research·Z Farooqi, P C Kesavan
Nov 1, 1995·International Journal of Radiation Oncology, Biology, Physics·J SeongG E Kim
May 30, 1998·Biochemical Pharmacology·C Stecca, G B Gerber
Nov 10, 2000·International Journal of Radiation Oncology, Biology, Physics·G P RaaphorstM Niedbala
Oct 4, 2006·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Morio Yonezawa
Dec 27, 2002·The Journal of General and Applied Microbiology·Kaberi Dutta
Nov 5, 2013·Antioxidants & Redox Signaling·Aris T Alexandrou, Jian Jian Li
Apr 30, 2009·International Journal of Radiation Biology·Lin LuYa Wang
Nov 1, 1993·International Journal of Radiation Biology·H Huang, H G Claycamp
Apr 1, 1994·International Journal of Radiation Biology·C Schäppi-Büchi
Mar 13, 2009·International Journal of Radiation Biology·Claudia A GrilloAlba M Guerci
May 1, 1993·International Journal of Radiation Biology·Y HosoiK Sakamoto
Aug 29, 2003·International Journal of Radiation Biology·D M Smith, G P Raaphorst
Aug 1, 1992·International Journal of Radiation Biology·W U MüllerF Niedereichholz
Mar 12, 2016·Redox Biology·Lingzhi BaoWei Han
Nov 9, 2004·Mutation Research·Tom K HeiMasao Suzuki
Jun 4, 1998·Clinical Oncology : a Journal of the Royal College of Radiologists·S C Short, M C Joiner
Mar 29, 2007·Radiation Research·Paula MaguireFiona M Lyng
Sep 8, 2016·International Journal of Radiation Biology·Marilyne StuartBrant Ulsh

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