Radio electric asymmetric conveyer: a novel neuromodulation technology in Alzheimer's and other neurodegenerative diseases

Frontiers in Psychiatry
Salvatore RinaldiVania Fontani

Abstract

Global research in the field of pharmacology has not yet found effective drugs to treat Alzheimer's disease (AD). Thus, alternative therapeutic strategies are under investigation, such as neurostimulation by physical means. Radio electric asymmetric conveyer (REAC) is one of these technologies and has, until now, been used in clinical studies on several psychiatric and neurological disorders with encouraging results in the absence of side effects. Moreover, studies at the cellular level have shown that REAC technology, with the appropriate protocols, is able to induce neuronal differentiation both in murine embryonic cells and in human adult differentiated cells. Other studies have shown that REAC technology is able to positively influence senescence processes. Studies conducted on AD patients and in transgenic mouse models have shown promising results, suggesting REAC could be a useful therapy for certain components of AD.

References

Jan 1, 2010·Journal of Alzheimer's Disease : JAD·Claudia BalducciGianluigi Forloni
Aug 9, 2011·Clinical Interventions in Aging·Alessandro CastagnaMatteo Lotti Margotti
Aug 9, 2011·Neuropsychiatric Disease and Treatment·Piero MannuAlessandro Castagna
Sep 21, 2011·Clinical, Cosmetic and Investigational Dermatology·Alessandro CastagnaPiero Mannu
Sep 29, 2011·Neuropsychological Rehabilitation·Paulo Sérgio BoggioFelipe Fregni
Dec 14, 2011·Patient Preference and Adherence·Vania FontaniSalvatore Rinaldi
Apr 23, 2013·Journal of Alzheimer's Disease : JAD·Javier OlazaránPablo Martínez-Martín
Jun 6, 2014·Journal of Alzheimer's Disease : JAD·Javier OlazaránPablo Martínez-Martín
Jun 12, 2014·Frontiers in Neurology·Niels Hansen

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Methods Mentioned

BETA
confocal microscopy

Software Mentioned

NPO
REAC

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