Radioactive seed localization versus wire localization for lumpectomies: a comparison of outcomes

AJR. American Journal of Roentgenology
Danielle SharekMarie A Ganott

Abstract

The purpose of this study was to compare outcomes of radioactive seed localization (RSL) versus wire localization using surgical margin size, reexcision and reoperation rates, specimen size, radiology resource utilization, and cosmesis as measures. Patients who underwent RSL before segmental mastectomy from April 1, 2011, to March 1, 2012, for biopsy-proven cancer were selected. Each was matched using tumor size, type, and surgeon to a wire localization control case, resulting in 232 cases. Width of the closest surgical margin, reexcision rate, and reoperation rate were compared as were the ratios of tumor volume to initial surgical specimen volume and tumor volume to all surgically excised volume (including reexcisions and reoperations). Cosmetic outcome was analyzed by comparison of Harvard scores and specimen volume with breast volume. Radiology resource utilization was compared before and after RSL implementation. No significant differences between methods were found in closest surgical margin (RSL mean, 0.45 cm; wire localization mean, 0.45 cm; p=0.972), reexcision rate (RSL mean, 21.1%; wire localization mean, 26.3%; p=0.360), reoperation rate (RSL, 11.4%; wire localization, 12.7%; p=0.841), ratio of the tumor volume to i...Continue Reading

Citations

Feb 6, 2016·Annals of Surgical Oncology·Charles E CoxSteven C Shivers
Aug 9, 2015·Annals of Surgical Oncology·James Jakub, Richard Gray
May 11, 2016·Journal of the American College of Radiology : JACR·Ray Cody Mayo, Jay R Parikh
Apr 17, 2017·Radiologic Clinics of North America·Mary K Hayes
Jul 15, 2017·The Breast Journal·Monica Da SilvaRoshni Rao
Jul 28, 2017·Journal of Surgical Oncology·Caitlin R PattenRichard L White
Jan 24, 2019·AJR. American Journal of Roentgenology·Alexandru NicolaeAnanth Ravi
Sep 21, 2017·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Vi Thuy TranIsabelle Trop
Sep 15, 2016·The American Journal of Surgical Pathology·Syed A Hoda
Oct 3, 2017·Archives of Pathology & Laboratory Medicine·Deborah O JeffriesJulie M Jorns
Dec 23, 2017·The British Journal of Radiology·Ellen CheangVictoria L Mango
Sep 12, 2020·Breast Cancer Research and Treatment·Santosh K SomasundaramJames Harvey
Jan 7, 2017·Annals of Surgical Oncology·Richard J GraySarah Blair
Sep 3, 2020·Annals of Surgical Oncology·Wyanne LawBelinda Curpen
Feb 2, 2019·The Breast Journal·Chelsea R HorwoodDoreen M Agnese
Sep 29, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Megha Madhukar KapoorMarion Elizabeth Scoggins
Oct 22, 2020·AJR. American Journal of Roentgenology·Leslie R LambConstance D Lehman
May 16, 2021·The Breast : Official Journal of the European Society of Mastology·Francesco GarzottoTania Saibene
Aug 13, 2021·International Journal of Computer Assisted Radiology and Surgery·Winona L RicheyMichael I Miga
Nov 6, 2017·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Jeremy S L OngDonna B Taylor

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.