Radioautographic localization of radioactivity in rat brain after intracarotid injection of 125I-alpha-melanocyte-stimulating hormone.

Pharmacology, Biochemistry, and Behavior
G PelletierA V Schally

Abstract

125I-alpha-melanocyte-stimulating hormone (MSH) was injected into the carotid artery of the rat and the radioactivity localized by radioautography. Radioactivity in the areas surrounding the ventricles and blood vessels after administration of 125I-alpha-MSH but not 125I-luteinizing hormone indicated passage of labeled material through the blood brain barrier. A specific concentration of radioactivity was found in the striatum and reticular nucleus of the thalamus. This localization, particularly in the thalamus, could be correlated with the previously reported effects of MSH on the brain of animals and man.

References

Oct 1, 1975·Physiology & Behavior·C A SandmanA J Kastin
Sep 1, 1974·Pharmacology, Biochemistry, and Behavior·L H MillerW J Van Veen
Dec 1, 1971·Physiology & Behavior·A J KastinM Velasco

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Citations

Jan 1, 1976·Pharmacology, Biochemistry, and Behavior·R GreenbergA J Kastin
Aug 1, 1978·Pharmacology, Biochemistry, and Behavior·T W ReddingD H Coy
Dec 1, 1979·Pharmacology, Biochemistry, and Behavior·A J KastinD H Coy
Jan 1, 1980·Neuroscience and Biobehavioral Reviews·G J LaHosteR D Olson
Jan 1, 1983·Pharmacology & Therapeutics·W G Clark, J M Lipton
Jul 1, 1985·Peptides·S T Shih, J M Lipton
Jan 1, 1995·Peptides·W A Banks, A J Kastin
Jan 1, 1976·Brain Research Bulletin·A J KastinA V Schally
Apr 1, 1985·Brain Research Bulletin·M Holdeman, J M Lipton
Jan 1, 1995·Brain Research Bulletin·S MiachonR Cespuglio
Oct 28, 1977·Annals of the New York Academy of Sciences·D de Wied
May 12, 2004·Peptides·William A Banks
Mar 26, 2015·Peptides·William A Banks
Jul 1, 1982·Medicinal Research Reviews·K Medzihradszky
May 1, 1980·Clinical Endocrinology·R A Donald
Apr 1, 1981·Journal of Endocrinological Investigation·A Bertolini, G L Gessa

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