PMID: 733585Oct 1, 1978Paper

Radiocardiographic procedures during the first passage of an intravascular tracer in diagnostic context with echo- and angiocardiography (author's transl)

Nuklearmedizin. Nuclear Medicine
W H Knapp

Abstract

In 107 patients having coronary artery disease in their majority, left ventricular ejection fraction and minimal cardiac transit times (MTT) were determined by precordial registration during the first passage of the radioactive tracer. 87 patients underwent echocardiographic examination. Data were compared with ventriculography and coronarography: left ventricular ejection fraction, if radiographically evaluated, shows a low sensitivity in indicating myocardial disorder. MTTs are reduced in more than 80% of patients with CAD at rest. With a few exceptions, all patients with disorders in the ventriculogram show reduced MTT values. MTTs, however, do not react specifically for myocardial performance. They also indicate disorders of central hemodynamics caused by vitia cordis. In these cases myocardial function can not be evaluated. Echocardiography can only be applied in about 85% of patients. It possesses a high sensitivity in discrimination of lower degree failures. Results are misleading in old infarctions with dyskinesia. It is concluded that best diagnostic information concerning global myocardial function results if direct hemodynamic parameters as MTT are combined with echocardiography.

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