PMID: 6170599Nov 1, 1981Paper

Radiochemical cross-linking between proteins and RNA within 70 S ribosomal particles from E. coli MRE600

International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine
N Giocanti, B Ekert

Abstract

In the absence of oxygen, gamma-irradiation produces covalent links between some ribosomal proteins and 16 S RNA to 23 S RNA, within 70 S ribosomes from E. coli MRE600. Under optimal conditions minimizing the structural modifications induced by radiations, in situ formed cross-links appear specific and reflect close RNA-protein contacts. In view of these results, the spatial organization of the 30 S, 50 S subunit interfaces is discussed. In addition, the gamma-irradiation technique reveals that subunit association induces modifications of some protein--RNA interactions.

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Citations

Aug 1, 1984·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·H Singh, J Bishop
Sep 1, 1986·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·B EkertR Sabattier
Aug 15, 1983·European Journal of Biochemistry·F J van de VenC W Hilbers

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