Radiofrequency ablation in children with asymptomatic Wolff-Parkinson-White syndrome

The New England Journal of Medicine
Carlo PapponeVincenzo Santinelli

Abstract

Ventricular fibrillation can be the presenting arrhythmia in children with asymptomatic Wolff-Parkinson-White syndrome. Deaths due to this arrhythmia are potentially preventable. We performed a randomized study in which prophylactic radiofrequency catheter ablation of accessory pathways was compared with no ablation in asymptomatic children (age range, 5 to 12 years) with the Wolff-Parkinson-White syndrome who were at high risk for arrhythmias. The primary end point was the occurrence of arrhythmic events during follow-up. Of the 165 eligible children, 60 were determined to be at high risk for arrhythmias. After randomization, but before any ablation had been performed, the parents withdrew 13 children from the study. Of the remaining children, 20 underwent prophylactic ablation and 27 had no treatment. The characteristics of the two groups were similar. There were three ablation-related complications, one of which led to hospitalization. During follow-up, 1 child in the ablation group (5 percent) and 12 in the control group (44 percent) had arrhythmic events. Two children in the control group had ventricular fibrillation, and one died suddenly. The cumulative rate of arrhythmic events was lower among children at high risk who ...Continue Reading

References

Nov 15, 1979·The New England Journal of Medicine·G J KleinJ J Gallagher
May 22, 1978·The American Journal of Cardiology·M E MantakasW W Miller
Jun 1, 1991·Journal of the American College of Cardiology·G F Van HareJ J Langberg
Aug 1, 1972·British Heart Journal·A C GiardinaM A Engle
Feb 28, 2002·The Journal of Pediatrics·Robert M CampbellJohn D Kugler
May 30, 2002·Journal of Cardiovascular Electrophysiology·John D KuglerUNKNOWN Pediatric Radiofrequency Ablation Registry of the Pediatric Radiofrequency Ablation Registry of the Pediatric Electrophysiol
Nov 7, 2003·The New England Journal of Medicine·Carlo PapponeSalvatore Rosanio

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Citations

Jul 28, 2005·Der Internist·J O Schwab, B Lüderitz
Jan 7, 2006·International Journal of Legal Medicine·Horst WedekindThomas Bajanowski
Nov 15, 2006·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·B Brembilla-PerrotN Zhang
Sep 24, 2008·Archives of Cardiovascular Diseases·Béatrice Brembilla-Perrot
Jan 7, 2005·The New England Journal of Medicine·John TriedmanGeorge Van Hare
Apr 28, 2009·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Béatrice Brembilla-PerrotFrançois Marçon
Aug 6, 2009·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Ryan G AleongDavid J Milan
Nov 3, 2009·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Francesco CantúUNKNOWN EHRA Scientific Initiatives Committee
Apr 30, 2013·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Jesper Hastrup SvendsenUNKNOWN Scientific Initiatives Committee, European Heart Rhythm Association
Jul 29, 2006·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Hein HeidbüchelUNKNOWN Study Group on Sports Cardiology of the European Association for Cardiovascular Prevention and Rehabilitation
Sep 8, 2012·Current Opinion in Pediatrics·Frank A Fish, Prince J Kannankeril
Aug 7, 2012·Interface Focus·Chi Hyung SeoMatthew O'Donnell
Nov 26, 2009·Pediatric Cardiology·Tammo DelhaasLivia Kapusta
Mar 23, 2013·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Guida SilvaVasco Gama
Dec 15, 2012·American Heart Journal·Justin P ZachariahLaura M Bevilacqua
Sep 1, 2012·Cardiac Electrophysiology Clinics·Manoj N ObeyesekereGeorge J Klein
Sep 1, 2012·Cardiac Electrophysiology Clinics·Carlo Pappone, Vincenzo Santinelli
Aug 11, 2015·Pacing and Clinical Electrophysiology : PACE·Michelle E KigerKathryn K Collins
Aug 19, 2008·Current Problems in Cardiology·Ken W LeeMelvin M Scheinman
Aug 29, 2007·Current Problems in Cardiology·Mintu Turakhia, Zian H Tseng
Sep 25, 2008·Pacing and Clinical Electrophysiology : PACE·Ashraf HarahshehPeter P Karpawich
Apr 2, 2009·Pacing and Clinical Electrophysiology : PACE·Giuseppe InamaMichele Gulizia
May 22, 2010·Pacing and Clinical Electrophysiology : PACE·Béatrice Brembilla-PerrotChristine Suty-Selton
Mar 1, 2012·Pacing and Clinical Electrophysiology : PACE·Louay Toni, Andrew D Blaufox
Sep 17, 2013·Pacing and Clinical Electrophysiology : PACE·Hyo Soon AnJung Yun Choi
Jun 15, 2011·Annales de cardiologie et d'angéiologie·F Benzakin, B Brembilla-Perrot
Jul 20, 2011·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Chi Hyung SeoMatthew O'Donnell
Jun 24, 2006·Annales de cardiologie et d'angéiologie·B Brembilla-Perrot
Jun 24, 2010·The American Journal of Medicine·Julia H Indik
Jan 10, 2006·Heart Rhythm : the Official Journal of the Heart Rhythm Society·George M McDaniel, George F Van Hare
Oct 11, 2005·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·V LucetI Denjoy
Sep 1, 2015·The American Journal of Emergency Medicine·Kyoung Hwan SongDong Hun Lee
Jan 21, 2015·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Roberto De PontiJorge A Salerno-Uriarte
Jan 17, 2009·Journal of the American College of Cardiology·Vincenzo SantinelliCarlo Pappone
Jan 17, 2009·Journal of the American College of Cardiology·Seshadri Balaji

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