Radiofrequency ablation in the treatment of small hepatocellular carcinoma: a meta analysis.

World Journal of Gastroenterology : WJG
Jun-Guo LiuZhi Du

Abstract

To evaluate survival and recurrence after radiofrequency ablation (RFA) for the treatment of small hepatocellular carcinoma (HCC) using a meta-analysis. Literature on RFA vs surgical resection for the treatment of small HCC published between January 1990 and December 2008 was retrieved. A meta-analysis was conducted to estimate pooled survival and recurrence ratios. A fixed or random effect model was established to collect the data. The differences in overall survival at 1-year, 3-years and at end of follow-up were not statistically significant between the RFA and surgery groups (P > 0.05). There were no differences in 1-year and 3-year recurrences between the RFA and surgery groups (P > 0.05). However, recurrence in the RFA group was lower than that in the surgery group up to the end of follow-up (P = 0.03). Survival was not significantly different. There was a significant difference in recurrences at the end of follow-up after RFA compared with surgical resection. RFA did not decrease the number of overall recurrences, and had no effect on survival when compared with surgical resection in a selected group of patients.

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Citations

Jun 4, 2013·European Journal of Radiology·Jianmin DingZhi Du
Jun 28, 2012·World Journal of Gastroenterology : WJG·Cai QiJie Yu
Oct 12, 2012·Surgical Endoscopy·Lisette T HoekstraThomas M van Gulik
Jul 7, 2011·Annals of Surgical Oncology·Roberto SantambrogioSavino Bruno
May 28, 2011·Journal of Vascular and Interventional Radiology : JVIR·Mark G van VledderJan N M Ijzermans
Nov 19, 2010·Ultrasound in Medicine & Biology·Roberto SantambrogioEnrico Opocher
Jun 26, 2015·Hepatology International·Chia-Chi Wang, Jia-Horng Kao
Mar 30, 2017·The Cochrane Database of Systematic Reviews·Avik MajumdarKurinchi Selvan Gurusamy
Oct 1, 2013·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Jong Sun KimSung Kyu Choi

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