Radiofrequency ablation of benign cold thyroid nodules: initial clinical experience

Thyroid : Official Journal of the American Thyroid Association
Young-sun KimSung Tae Kim

Abstract

To evaluate the efficacy and safety of ultrasound (US)-guided percutaneous radiofrequency (RF) ablation for benign cold thyroid nodules as a nonsurgical therapeutic modality. DESIGN, INTERVENTION, AND PATIENTS: A total of 35 benign cold thyroid nodules in 30 euthyroid patients (M:F = 2:28; mean age 39.1 years) underwent percutaneous RF ablation with a 1-cm-internally cooled electrode. Seventy-seven percent (23/30) of patients required conscious sedation for discomfort. We evaluated the tumor size, cystic component, vascularity (by color Doppler US), and the severity of mass-related symptoms before treatment. We assessed the therapeutic efficacy and safety of RF ablation by clinical and US follow-up (median 6.4 months). The volume of the tumors before ablation had a range of 0.6-28.2 mL (mean, 6.3 mL). The residual volume was 53.5% +/- 26.5% of original at 1.1-2.9 months (n = 32), 36.2% +/- 27.4% at 3.0-5.9 months (n = 20), 30.7% +/- 25.0% at 6.0-8.9 months (n = 15), and 11.8% +/- 10.9% at 9.0-18.5 months (n = 13). Mixed/mainly cystic tumors showed a significantly better response than mainly solid tumors (p < 0.05). Difference in vascularity did not affect the treatment response. Thyroid function after the procedure was maintain...Continue Reading

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Citations

Jun 27, 2008·Thyroid : Official Journal of the American Thyroid Association·Jung Hwan BaekDucky Lee
Mar 7, 2009·Thyroid : Official Journal of the American Thyroid Association·Stefano SpieziaAntongiulio Faggiano
Oct 12, 2010·Thyroid : Official Journal of the American Thyroid Association·Roberto ValcaviClaudio M Pacella
Aug 13, 2011·Thyroid : Official Journal of the American Thyroid Association·Olivier EsnaultLaurence Leenhardt
Sep 28, 2012·Thyroid : Official Journal of the American Thyroid Association·Eun Ju HaYoung Kee Shong
Aug 23, 2011·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Lucy B Wallace, Eren Berber
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Jul 26, 2011·AJR. American Journal of Roentgenology·Jung Hwan BaekJeong Hyun Lee
Dec 4, 2013·International Journal of Endocrinology·Kai-Pun Wong, Brian Hung-Hin Lang
Nov 8, 2012·International Journal of Endocrinology·Ji Hoon ShinJeong Hyun Lee
Jun 20, 2014·Future Oncology·Yin-Long YangXiao-Hua Zhang
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Nov 13, 2015·Thyroid : Official Journal of the American Thyroid Association·Stella BernardiFulvio Stacul
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Aug 27, 2009·Lasers in Surgery and Medicine·Jörg-P RitzChristoph Holmer
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Aug 8, 2015·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Mark A Lupo

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