Radiofrequency ablation of hepatocellular carcinoma in patients with decompensated cirrhosis: evaluation of therapeutic efficacy and safety

AJR. American Journal of Roentgenology
Young Kon KimJeong Min Lee

Abstract

Our objective was to determine the therapeutic efficacy and safety of radiofrequency ablation in the treatment of hepatocellular carcinoma (HCC) in patients with decompensated cirrhosis. Nineteen patients with 26 HCC nodules (range, 0.8-5 cm; mean, 1.96 cm) and decompensated liver cirrhosis (mean Child score, 10.7) were treated with radiofrequency ablation using cooled-tip electrodes and a 200-W generator. Radiofrequency ablation was performed under the guidance of sonography or CT. Procedure-related complications, therapeutic efficacy, each patient's survival, changes in blood test results--that is, serum aminotransferase and bilirubin--and changes in the Child score before and after ablation therapy were analyzed. To assess the therapeutic response of the tumor to radiofrequency ablation, we performed contrast-enhanced CT after the procedure and during follow-up. Complete necrosis without marginal recurrence at the 6-month follow-up was attained in 23 lesions (88.5%). During follow-up (mean, 13.3 months), one patient experienced a remote tumor recurrence in the liver. The median survival time was 12.0 +/- 1.7 months. Two patients died of liver failure--one at 2 months and one at 4 months after treatment. The other patients we...Continue Reading

References

Apr 1, 1992·American Journal of Surgery·H BismuthA Roche
Oct 1, 1985·Annals of Surgery·S IwatsukiT E Starzl
Jan 1, 1993·Digestive Diseases and Sciences·K N KhanS Nagataki
Jun 24, 1993·The New England Journal of Medicine·H TsukumaH Yamazaki
May 1, 1995·AJR. American Journal of Roentgenology·R MurakamiK Sagara
Mar 1, 1994·Annals of Surgery·D G FarmerR W Busuttil
Jul 1, 1995·Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·A P VenookJ R Lake
Sep 1, 1995·Academic Radiology·S N GoldbergT C McLoud
Apr 8, 1998·AJR. American Journal of Roentgenology·S RossiL Buscarini
Sep 10, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Oct 22, 1998·The British Journal of Surgery·E A AkriviadisW C Meyers
Aug 6, 1999·Journal of Vascular and Interventional Radiology : JVIR·S N GoldbergM E Clouse
Oct 13, 1999·Seminars in Liver Disease·J M LlovetJ Bruix
Sep 19, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J M Llovet, J Bruix
Dec 9, 2000·Radiology·G S GazelleT Livraghi
Jan 3, 2001·AJR. American Journal of Roentgenology·J P McGhana, G D Dodd
Mar 5, 2003·Seminars in Liver Disease·Robert J Fontana
Jun 5, 2003·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Ivo W GraziadeiWolfgang Vogel
Jun 27, 2003·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Francis Y YaoJohn P Roberts
Dec 16, 2003·Journal of Hepatology·Umberto CilloDavide Francesco D'Amico
Feb 3, 2004·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Andrew Paul KeavenyUrmila Khettry
Feb 6, 2004·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Josep M LlovetUNKNOWN Barcelona-Clínic Liver Cancer Group

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