Radiofrequency ablation of liver metastases from colorectal carcinoma

Cancer Control : Journal of the Moffitt Cancer Center
Eric C Feliberti, Lawrence D Wagman

Abstract

Most patients with colorectal carcinoma will develop liver metastases. Radiofrequency ablation (RFA) has been utilized in metastatic CRC to help improve the survival gap between resectable and unresectable tumor. The current use of RFA in selected patient populations is reviewed. RFA provides a survival benefit in patients with unresectable hepatic metastases from CRC compared with chemotherapy alone. It offers effective local tumor destruction in appropriately selected lesions and minimizes the morbidity and mortality of an open resection. Common complications are abdominal bleeding (1.6%), abdominal infection (1.1%), and injury to the biliary tree (1.0%). Mortality ranges from 0% to 0.5%. Trials are underway to compare chemotherapy plus local ablation to chemotherapy alone. RFA is a tool that should be utilized by experienced individuals to achieve optimal oncologic outcomes.

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Citations

Jun 1, 2010·Journal of Surgical Oncology·Mahmoud N Kulaylat, John F Gibbs
Sep 23, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Suzanne Claire SchiffmanCharles R Scoggins
Nov 9, 2011·Journal of the Korean Surgical Society·Kyung Ho KimJin Cheon Kim
Feb 28, 2014·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Vanni LoprestoMarta Cavagnaro
Aug 23, 2006·Future Oncology·Derek A O'Reilly, Graeme J Poston
Jun 15, 2012·The Cochrane Database of Systematic Reviews·Roberto CirocchiIosief Abraha
Jan 24, 2007·Technology in Cancer Research & Treatment·Boris RubinskyPaul Mikus
Mar 2, 2006·Cancer Control : Journal of the Moffitt Cancer Center·James M McLoughlinMokenge Malafa
Dec 1, 2010·Indian Journal of Surgical Oncology·Samir Pathak, Graeme J Poston
Mar 5, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Yunzhu DaiRuhai Zou
Mar 21, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·I M C van der PloegR van Hillegersberg
Nov 21, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·C NesbittG J Poston
Aug 9, 2011·Clinical Colorectal Cancer·Steven R Alberts, Graeme J Poston

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