Radiofrequency ablation of peripheral liver tumors: intraperitoneal 5% dextrose in water decreases postprocedural pain

AJR. American Journal of Roentgenology
J Louis HinshawFred T Lee

Abstract

Our objective was to evaluate the clinical efficacy of the intraperitoneal instillation of 5% dextrose in water (D5W) during radiofrequency ablation of peripheral liver tumors for decreasing postradiofrequency pain and narcotic use. This case-control study compared the hospital course of the last 20 patients to undergo radiofrequency ablation of peripheral liver tumors at our institution. Ten consecutive subjects in the D5W group (seven women and three men; age range, 37-78 years; mean, 58 years) were pretreated with intraperitoneal D5W (average, 963 +/- 436 [SD] mL) before the ablation. This group was compared with a control group of 10 patients (five men and five women; age range, 36-73 years; mean, 54 years) who did not receive intraperitoneal D5W. The size of the ablation zone, degree of liver capsule involvement, number of burns, patient-reported pain, patient-controlled analgesia use, and length of hospital stay were recorded and compared between the groups. The patients in the D5W group reported significantly less pain in the first 24 hr after the procedure than did the controls (2.3 vs 6.3, p = 0.003) despite a significant decrease in patient-controlled analgesia use (17.3 vs 125.1 mg of morphine, p = 0.003). The differ...Continue Reading

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Citations

Aug 21, 2008·Journal of Gastroenterology and Hepatology·Hyunchul RhimWon Jae Lee
Aug 21, 2009·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Masashi HirookaMorikazu Onji
Aug 24, 2007·AJR. American Journal of Roentgenology·J Louis HinshawFred T Lee
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