Radiofrequency ablation versus hepatic resection for the treatment of hepatocellular carcinomas 2 cm or smaller: a retrospective comparative study

Radiology
Zhen-Wei PengMin-Shan Chen

Abstract

To compare retrospectively the effects of percutaneous radiofrequency (RF) ablation with those of hepatic resection in the treatment of hepatocellular carcinoma (HCC) measuring 2 cm or smaller. This study was approved by the institutional ethics committee, and all patients provided written informed consent before treatment. From December 2003 to December 2008, 145 patients with a resectable HCC measuring 2 cm or smaller were studied. Sixty-six patients had a central HCC (located at least 3 cm from the liver capsule). As an initial treatment, 71 patients were treated with percutaneous RF ablation and 74 with surgical resection. Of the patients with central HCC, 37 underwent percutaneous RF ablation and 29 underwent surgical resection. Survival curves were constructed with the Kaplan-Meier method and compared by using the log-rank test. The relative prognostic significance of the variables for predicting overall survival rates was assessed with multivariate Cox proportional hazards regression analysis. Complications were observed clinically when patients were admitted and assessed by telephone interview after patients were discharged. One death was considered to be related to treatment after surgical resection. Major complication...Continue Reading

References

Mar 1, 1989·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·T MatsumataK Sugimachi
Dec 1, 1982·American Journal of Clinical Oncology·M M OkenP P Carbone
Jan 1, 1981·Cancer·A B MillerA Winkler
Jun 24, 2000·JAMA : the Journal of the American Medical Association·H G WelchS Woloshin
May 9, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J M LlovetUNKNOWN Barcelona Clínic Liver Cancer (BCLC) Group
Apr 2, 2002·The American Journal of Gastroenterology·Franco TrevisaniUNKNOWN Italian Liver Cancer Group
Jul 13, 2002·Journal of Surgical Oncology·Frederick L Greene, Leslie H Sobin
Oct 3, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Francis Y YaoJohn P Roberts
Dec 12, 2003·Lancet·Josep M LlovetJordi Bruix
Mar 17, 2004·World Journal of Surgery·Ming ShiJin-Qing Li
Oct 28, 2004·Gastroenterology·Myron Schwartz
Oct 28, 2004·Gastroenterology·Giovanna FattovichFrancesco Donato
Apr 23, 2005·Radiology·S Nahum GoldbergUNKNOWN International Working Group on Image-Guided Tumor Ablation
Jun 24, 2005·American Journal of Surgery·Emma J MullinGuy J Maddern
Oct 27, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jordi BruixUNKNOWN Practice Guidelines Committee, American Association for the Study of Liver Diseases
Jan 5, 2006·JAMA : the Journal of the American Medical Association·Chien-Jen ChenUNKNOWN REVEAL-HBV Study Group
Mar 15, 2006·Gastroenterology·Uchenna H IloejeUNKNOWN Risk Evaluation of Viral Load Elevation and Associated Liver Disease/Cancer-In HBV (the REVEAL-HBV) Study Group
Nov 17, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Tito LivraghiSandro Rossi
Nov 22, 2007·Liver International : Official Journal of the International Association for the Study of the Liver·Beom Kyung KimSang Hoon Ahn
Jul 12, 2008·The American Journal of Gastroenterology·Ivan F N HungMan-Fung Yuen
Sep 15, 2009·Journal of Hepatology·Jaw-Ching WuWing-Yiu Lui

❮ Previous
Next ❯

Citations

Aug 21, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jianyong LeiLunan Yan
Apr 9, 2013·Annals of Surgical Oncology·Eldad ElnekaveAnne M Covey
Jul 19, 2013·World Journal of Gastroenterology : WJG·Alessandro CucchettiAntonio Daniele Pinna
Mar 16, 2013·World Journal of Radiology·Paola TombesiSergio Sartori
Apr 20, 2014·World Journal of Gastroenterology : WJG·Jong Man KimSeung Woon Paik
Nov 7, 2014·Cardiovascular and Interventional Radiology·Roberto Luigi CazzatoJean Palussière
Oct 20, 2015·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Neil MehtaFrancis Y Yao
Aug 1, 2015·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·John T MiuraT Clark Gamblin
Mar 6, 2016·Journal of the American College of Radiology : JACR·Brian E KouriEric J Hohenwalter
Nov 26, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Fei TianYun-He Liu
May 17, 2015·Current Problems in Diagnostic Radiology·Toshimasa ClarkPuneet Bhargava
Jan 24, 2015·Scandinavian Journal of Gastroenterology·Ilana GoryUNKNOWN Melbourne Liver Group
Mar 20, 2014·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jeong Hee YoonByung Ihn Choi
Dec 17, 2015·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Toshiro MasudaHideo Baba
Sep 30, 2016·Journal of Hepatology·Alessandro VitaleTimothy M Pawlik
May 18, 2016·Liver International : Official Journal of the International Association for the Study of the Liver·Wei HeYunfei Yuan
Nov 23, 2016·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Anna PoupalouPeriklis Tomos
Dec 22, 2012·Digestive Diseases·Shinobu TsuchidaMasatoshi Kudo
Apr 28, 2018·AJR. American Journal of Roentgenology·Jeffrey L Weinstein, Muneeb Ahmed
Nov 22, 2016·World Journal of Gastrointestinal Pharmacology and Therapeutics·Antonio FacciorussoNicola Muscatiello
May 29, 2018·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Xiong-Ying JiangJin-Hua Huang
Sep 12, 2018·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Min DingBo Zhai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.