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Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-controlled, 52-week trial

Arthritis and Rheumatism

May 18, 2004

Edward KeystoneElliot K Chartash

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Abstract

Tumor necrosis factor (TNF) is an important proinflammatory cytokine that mediates inflammatory synovitis and articular matrix degradation in rheumatoid arthritis (RA). We investigated the ability of adalimumab, a human anti-TNF monoclonal antibody, to inhibit the progression of structu...read more

Mentioned in this Paper

Monoclonal Antibodies
Necrosis
Antirheumatic Drugs, Disease-Modifying
Tumor Necrosis Factor-alpha
Humira
Polychemotherapy
Joints
Adverse Event
Rheumatoid Arthritis
Cytokine
269
Paper Details
References
  • References5
  • Citations556
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Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-controlled, 52-week trial

Arthritis and Rheumatism

May 18, 2004

Edward KeystoneElliot K Chartash

PMID: 15146409

DOI: 10.1002/art.20217

Abstract

Tumor necrosis factor (TNF) is an important proinflammatory cytokine that mediates inflammatory synovitis and articular matrix degradation in rheumatoid arthritis (RA). We investigated the ability of adalimumab, a human anti-TNF monoclonal antibody, to inhibit the progression of structu...read more

Mentioned in this Paper

Monoclonal Antibodies
Necrosis
Antirheumatic Drugs, Disease-Modifying
Tumor Necrosis Factor-alpha
Humira
Polychemotherapy
Joints
Adverse Event
Rheumatoid Arthritis
Cytokine
269

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Related Papers

Paper Details
References
  • References5
  • Citations556
12345...

Download from

Publisher
PubMed
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