PMID: 25774580Mar 17, 2015Paper

Radiographic disappearance of lanthanum

Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia
Giordano Pastori

Abstract

In 2006, Cerny and Kunzendorf in the New England Journal of Medicine Images in clinical medicine, showed the radiographic appearance of lanthanum for the first time. After many years we noticed the inverse phenomenon. In a peritoneal dialysis patient treated with lanthanum carbonate, we had two radiography of the abdomen for monitoring the peritoneal catheter. In the first radiography contrast material was seen in colon. In the most recent radiography contrast material disappeared. The patient was always taking the same dose of lanthanum carbonate (1000 mg bid), although at the time of the first radiography he took the chewable tablets, for the last radiography he took the new powder formulation. We found a report in literature highlighting this phenomenon meanwhile indicating a greater chelating effect for the powder. Our hypothesis is that despite the same lanthanum dose, powder provides a greater surface area of binding and a more dispersed bowel distribution to explain a masked radio-opacity. Considering the wide availability of the powder, this must be taken into account especially in evaluating therapeutic compliance.

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The New England Journal of Medicine
Simon Cerny, Ulrich Kunzendorf
Nefrología : publicación oficial de la Sociedad Española Nefrologia
José R Rodríguez-PalomaresSerafín Tallón
Néphrologie & thérapeutique
Laurence VrigneaudVincent Lemaitre
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Alan Ali Moazzam, Sarinya Boongird
© 2021 Meta ULC. All rights reserved