Radiographic joint space width in the fingers of patients with rheumatoid arthritis of less than one year's duration

Arthritis and Rheumatism
Ewan C GoligherAxel Finckh

Abstract

To determine the radiographic joint space width (JSW) in undamaged metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joints of patients with early rheumatoid arthritis (RA) and to identify important clinical determinants of JSW. Radiographs of patients with RA of <1 year's duration, from an early arthritis cohort at a tertiary care rheumatology clinic, were obtained. JSW was analyzed by joint, finger, age, sex, height, and a number of other clinically relevant variables. Multivariate analysis was also performed, to account for possible confounding between variables. Thirty-eight patients were included in the study. We found that JSW was greater in the MCP joint than the PIP joint (P < 0.0001). JSW was significantly greater in men (P < 0.0001) and increased with increasing height (P < 0.003), but was not associated with age (P < 0.21). In multivariate analyses, sex was shown to be the most important predictor of JSW. In patients with early RA, MCP and PIP JSW is significantly associated with sex and height. In studies of RA in which JSW measurements are included as an outcome, these differences may need to be accounted for in the analysis.

Citations

Jun 30, 2011·Computer Methods in Biomechanics and Biomedical Engineering·Kent D ButzEric A Nauman
Feb 15, 2013·Arthritis Research & Therapy·Alexander PfeilJoachim Böttcher
Sep 3, 2013·Hand : Official Journal of the American Association for Hand Surgery·Kent D ButzEric A Nauman
Jan 1, 2009·IEEE Transactions on Medical Imaging·Georg LangsFranz Kainberger
Jan 6, 2016·IEEE Transactions on Bio-medical Engineering·Yinghe HuoMax A Viergever
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Oct 20, 2010·Arthritis Care & Research·Gesa NeumannJeffrey Duryea
Sep 8, 2017·RMD Open·Michael PlattenRonald van Vollenhoven
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Apr 1, 2009·Arthritis and Rheumatism·Burkhard MöllerHans-Rudolf Ziswiler

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