PMID: 6106787Sep 27, 1980Paper

Radioimmunoassay of serum creatine kinase-BB as a tumour marker in breast cancer

Lancet
R J ThompsonH M Jones

Abstract

Brain type creatine kinase-BB (CPK-BB) was measured by radioimmunoassay in the serum of 113 women with breast cancer and 354 female controls. 80% of women with metastatic breast cancer had levels above 3 ng/ml (control range 0.5--3.7 ng/ml); the highest level was 23 ng/ml. 60% of women with local disease but no evidence of distant metastases showed levels above 3 ng/ml, the highest being 9.0 ng/ml. Of women who had presented with stage I, II, or III disease and postoperatively had no evidence of persistent disease 30% had levels above 3 ng/ml. Serial measurements in 31 patients indicated that the serum CPK-BB correlated with clinical response to treatment.

References

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Citations

Feb 23, 2000·Analytical Biochemistry·E M TowlerR J Fisher
May 1, 1990·Breast Cancer Research and Treatment·R L CerianiT Trujillo
Jul 28, 2012·Journal of Bioenergetics and Biomembranes·Tuuli KaambreValdur Saks
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Jan 31, 1984·Clinica Chimica Acta; International Journal of Clinical Chemistry·I N Day, R J Thompson
Apr 15, 1987·Clinica Chimica Acta; International Journal of Clinical Chemistry·A UsuiK Kato
Jun 30, 1988·Clinica Chimica Acta; International Journal of Clinical Chemistry·A UsuiA Yamaguchi
Jun 30, 1989·Clinica Chimica Acta; International Journal of Clinical Chemistry·J ArenasJ M Culebras
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Nov 1, 1991·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·L M Lin, Y K Chen
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Jan 1, 1983·Critical Reviews in Clinical Laboratory Sciences·J C Griffiths
Oct 1, 1985·Scandinavian Journal of Clinical and Laboratory Investigation·P Urdal, J H Stromme
Mar 30, 2016·Amino Acids·Yong-Bin Yan
Feb 1, 1983·Muscle & Nerve·A A Nanji
Jan 1, 1983·Acta Medica Scandinavica·S Ström, R Bendz
Mar 1, 1996·Annals of Clinical Biochemistry·M CrookR Swaminathan
Apr 1, 1990·Molecular and Cellular Biology·R Kaddurah-DaoukP Schimmel
Oct 1, 1995·Respiratory Medicine·D Ferrigno, G Buccheri
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Feb 1, 1983·Clinical Biochemistry·M K Schwartz
Jul 30, 2021·Analytical Methods : Advancing Methods and Applications·Shivanshu Mishra, Nidhi Chaturvedi

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