PMID: 517980May 1, 1979Paper

Radioimmunoassay of trypsin. A new aid in the assessment of pancreatic function

Annals of Clinical Biochemistry
B H Stagg, T P Wood

Abstract

This review describes the development and application of a novel test to determine levels of human immunoreactive trypsin, an enzyme produced solely by the pancreas, in biological fluids. Being organ-specific, the assay of immunoreactive trypsin should be an ideal marker of pancreatic function, and this is supported by the results of a number of clinical and research investigations. Use of this assay in studies of chronic pancreatitis, juvenile-onset diabetes, and cystic fibrosis has yielded much valuable data, and it is expected that further research will lead to an improved understanding of these and other conditions associated with the pancreas in health and disease.

References

Oct 15, 1977·Clinica Chimica Acta; International Journal of Clinical Chemistry·P T BrayJ D Thomas
Nov 26, 1977·Lancet·J R CrossleyR B Elliott
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Mar 1, 1977·Annals of Clinical Biochemistry·A H Gowenlock
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Aug 1, 1974·Archives of Disease in Childhood·R ProsserJ Dathan

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Citations

Dec 1, 1989·The British Journal of Surgery·P A ClavienA R Moossa
Jun 1, 1985·Digestive Diseases and Sciences·C LesiP Malaguti
Jan 1, 1989·Digestive Diseases and Sciences·M VentrucciL Barbara
Jul 1, 1980·Clinica Chimica Acta; International Journal of Clinical Chemistry·M D O'Donnell, N J Miller
Jan 15, 1981·Biochimica Et Biophysica Acta·C H Lawrence, B J Morris

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