Radioimmunological quantitation of the urinary trypsin inhibitor in normal blood and urine.

Biological Chemistry Hoppe-Seyler
B M Jönsson-BerlingM Rosengren

Abstract

A radioimmunoassay for measurement of the urinary trypsin inhibitor in human serum and urine is described. Because of the immunological cross-reactivity between the inter-alpha-trypsin inhibitor and the urinary trypsin inhibitor the plasma and serum were treated with perchloric acid to precipitate the inter-alpha-trypsin inhibitor. Gel filtration of serum before and after acid treatment showed identical peaks corresponding to the urinary trypsin inhibitor. The normal level of the urinary trypsin inhibitor in fresh plasma from 30 blood donors was 6.38 +/- 0.33 mg/l (SEM), and in sera from 24 healthy volunteers 7.14 +/- 0.27 mg/l (SEM). In urine from 23 healthy volunteers the normal excretion was 8.17 +/- 1.18 mg/24 h (SEM).

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Citations

Jun 1, 1994·Clinica Chimica Acta; International Journal of Clinical Chemistry·T ShikimiS Takaori
Apr 23, 2002·Journal of Gastroenterology and Hepatology·Shi De LinKazuyuki Suzuki
Feb 1, 1994·Biological Chemistry Hoppe-Seyler·A SłotaE Fries
Sep 5, 2002·Clinical Chemistry and Laboratory Medicine : CCLM·Charlotte MizonJacques Mizon
Mar 13, 2001·Biochemical and Biophysical Research Communications·H SatoJ Miyazaki
May 5, 2001·Scandinavian Journal of Gastroenterology·T NoieM Makuuchi
Apr 7, 2010·Expert Opinion on Investigational Drugs·Ken-ichiro Inoue, Hirohisa Takano
Nov 21, 2007·Journal of Bioscience and Bioengineering·Masaaki UekiNobuhiro Maekawa
Jan 2, 2013·Korean journal of anesthesiology·Seong-Heon LeeSanghee Park
Dec 6, 2016·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Ming LiuMingxia Fan
Oct 1, 1991·Scandinavian Journal of Clinical and Laboratory Investigation·B M Jönsson-Berling, K Ohlsson
Nov 27, 2008·Journal of Intensive Care Medicine· Li YuminE E Frezza
Sep 4, 1999·Clinical and Experimental Pharmacology & Physiology·T ShikimiS Takaori
Nov 13, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Perenlei Molor-ErdeneHiroaki Okabe
Oct 1, 2017·Experimental and Therapeutic Medicine·Wen-Ke WangYi-Meng Du

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