PMID: 8940708Aug 1, 1996Paper

Radiolabeled peptides and other ligands for receptors overexpressed in tumor cells for imaging neoplasms

Nuclear Medicine and Biology
J G McAfee, R D Neumann

Abstract

For better detection of neoplasms by scintigraphy, ligands that bind specifically to surface receptors overexpressed in tumor cells are being developed. These ligands must be labeled with the readily available radionuclides of iodine, [111In] or [99mTc], without blocking their interaction with the specific cell membrane receptors. The promising ligands include bioactive endogenous peptides or their analogues, inhibitors of glucose transport proteins, estrogen and sigma receptor ligands, growth factors, and cytokines.

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Citations

Nov 16, 2002·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Ronald E Weiner, Mathew L Thakur
May 9, 2003·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·K K KothariW A Volkert
Oct 2, 2001·Nuclear Medicine and Biology·R RossinU Mazzi
Jan 12, 2002·Nuclear Medicine and Biology·Ralf BergmannBernd Johannsen
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Jun 30, 2005·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Ronald E Weiner, Mathew L Thakur
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Nov 28, 2013·Toxicological Research·Beom-Su JangSang Hyun Park
Oct 10, 2018·Chemical Biology & Drug Design·Farzaneh Rezazadeh, Nourollah Sadeghzadeh
Feb 2, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Narottam LamichhaneJaved Mahmood
Jun 4, 2013·Investigational New Drugs·Alexander SturzuStefan Heckl
Sep 17, 2019·Life Sciences·Sajjad Ahmadpour, Seyed Jalal Hosseinimehr
Dec 26, 2001·Chemical Reviews·S Liu, D S Edwards
Mar 15, 2011·Journal of Medicinal Chemistry·Verena M AhrensEvamarie Hey-Hawkins
Apr 20, 2001·Journal of Medicinal Chemistry·M LangerA G Beck-Sickinger

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