Radiological and pathological diagnosis of paediatric bone tumours and tumour-like lesions

Pathology
M Vlychou, N A Athanasou

Abstract

Primary bone tumours are rare but account for a significant proportion of cancers occurring in childhood and adolescence. Malignant bone tumours need to be distinguished not only from their benign counterparts but also from tumour-like lesions, many of which are developmental or reactive in nature and are found commonly in the paediatric population. Taking note of the age of the patient and the site of the lesion within bone (aided by several imaging techniques including plain radiographs, ultrasound, computed tomography, bone scintigraphy and magnetic resonance imaging) is essential for pathological diagnosis. Immunohistochemistry, cytogenetics, molecular analysis and other techniques are now powerful diagnostic tools in bone pathology. This review aims to provide an approach to the radiological and pathological diagnosis of paediatric bone tumours. It also provides a brief overview of some of the more common bone tumours and tumour-like lesions, both benign and malignant, which occur in childhood and adolescence.

References

Nov 1, 1977·The Journal of Bone and Joint Surgery. British Volume·F Schajowicz
Aug 1, 1978·The Journal of Bone and Joint Surgery. British Volume·G A Evans, W M Park
Sep 1, 1992·Radiographics : a Review Publication of the Radiological Society of North America, Inc·C L SuttonS B Gay
Jan 1, 1992·Skeletal Radiology·M H Klein, S Shankman
May 1, 1992·Journal of Pediatric Orthopedics·D KeretD E Mason
Jun 15, 1992·Cancer·A M Vergel De DiosK K Unni
Nov 1, 1991·Cancer·C Y InwardsF H Sim
Aug 1, 1987·Journal of Clinical Pathology·N A AthanasouJ O McGee
Aug 1, 1988·Neurologia Medico-chirurgica·T YokoyamaT Orita
May 1, 1985·Journal of Pediatric Orthopedics·M C LeesonJ R Carter
Dec 1, 1987·The American Journal of Medicine·N D ChomaA A Licata
Sep 1, 1986·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·R ChuongA Perez-Atayde
Jul 1, 1986·The American Journal of Surgical Pathology·L E WoldD C Dahlin
Mar 1, 1986·Clinical Orthopaedics and Related Research·M CampanacciP Picci
Dec 1, 1984·The American Journal of Surgical Pathology·R JaffeM Goodman
Jan 1, 1984·Skeletal Radiology·D C DahlinM Campanacci
Nov 1, 1983·The Journal of Bone and Joint Surgery. British Volume·M ChigiraE Udagawa
Mar 1, 1984·The American Journal of Surgical Pathology·J BjornssonF H Sim
Sep 1, 1982·Cancer·S E MartinJ Costa
Oct 1, 1980·Seminars in Roentgenology·B R ParkerR A Castellino
Jan 15, 1982·Cancer·L N NewcomerL R Prosnitz
Jan 1, 1982·Current Topics in Pathology. Ergebnisse Der Pathologie·A Roessner, E Grundmann
Jun 1, 1980·The American Journal of Surgical Pathology·E F McCarthy, H D Dorfman
Apr 1, 1995·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·R J Grimer, S R Carter
Mar 1, 1995·AJR. American Journal of Roentgenology·M J Kransdorf, D E Sweet
Oct 1, 1994·Journal of Neurosurgery·M J RutiglianoA L Albright
Jul 1, 1994·The British Journal of Radiology·R S DaviesA Pierro
Mar 1, 1994·Cancer·P RuggieriK K Unni
Feb 1, 1994·Human Pathology·D R LucasF H Sim
Apr 1, 1994·Human Pathology·M RiopelE J Perlman
Dec 1, 1993·Human Pathology·Y K ParkD J Pritchard
Dec 1, 1993·Cancer Genetics and Cytogenetics·L SainatiG Basso
Jul 1, 1993·Cancer Genetics and Cytogenetics·M TarkkanenS Knuutila
Aug 1, 1993·The American Journal of Surgical Pathology·I V BulychovaJ W Beabout

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Citations

Mar 13, 2010·Pediatric Radiology·Mary R Wyers
Mar 16, 2013·Pediatric Surgery International·Yelda JozaghiMiriam Blumenkrantz
Aug 28, 2009·La Chirurgia degli organi di movimento·Henry J MankinCarole J Mankin
Apr 13, 2000·Australasian Radiology·P Corr
Mar 11, 2010·JAAPA : Official Journal of the American Academy of Physician Assistants·Jason R Smith, Richard Davidson
May 23, 2012·Clinical Sarcoma Research·D Charles Mangham, Nicholas A Athanasou
Nov 23, 2013·AJR. American Journal of Roentgenology·Evan J ZuckerRonald L Eisenberg
Jan 3, 2012·European Journal of Radiology·Claudio Granata, Gianmichele Magnano
Dec 15, 2011·Seminars in Roentgenology·Geetika Khanna, D Lee Bennett
Jun 16, 2009·Magnetic Resonance Imaging Clinics of North America·Sandra L Wootton-Gorges
May 29, 2012·Pediatric Hematology and Oncology·Anand PrakashSatya Prakash Yadav
Apr 27, 2012·Physiological Reviews·Michelle L James, Sanjiv S Gambhir

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