Radiological Management of Angiographically Negative, Spontaneous Intracranial Subarachnoid Hemorrhage: A Multicenter Study of Utilization and Diagnostic Yield

Neurosurgery
Gelareh SadighJason W Allen

Abstract

The optimal diagnostic evaluation for patients with angiographically negative subarachnoid hemorrhage (AN-SAH) remains controversial. To assess the utilization rate and diagnostic yield of imaging tests routinely obtained in identifying a structural cause for AN-SAH. In this retrospective multicenter study, consecutive adult patients admitted with nontraumatic, AN-SAH between 01/2010 and 12/2015 were included. Patients with intraparenchymal, subdural, or epidural hematomas in addition to SAH were excluded. Outcomes studied included utilization rate, diagnostic yield, and median time from admission for the following imaging tests: initial computed tomography angiography (CTA) and digital subtraction angiography (DSA), brain and cervical spine magnetic resonance imaging (MRI), and any repeat DSA or CTA performed either during initial admission or at long-term follow-up. A total of 752 patients were included (mean age, 53 yr; 54% male). Initial CTA and DSA were performed in 89% and 100% of patients, respectively. Brain MRI was performed in 75% of patients and was positive in 0.7% of cases. Cervical spine MRI was performed in 61% of patients and was positive in 0.2% of cases. Repeat, same-admission follow-up DSA and CTA were perfor...Continue Reading

References

Mar 1, 1986·Journal of Neurosurgery·R JuulR Ringkjøb
Jan 1, 1994·British Journal of Neurosurgery·N PathiranaK E Bell
Aug 1, 1994·Neuroradiology·S A RenowdenJ V Byrne
Jul 1, 1994·Stroke; a Journal of Cerebral Circulation·J P BroderickA Leach
Sep 1, 1993·Stroke; a Journal of Cerebral Circulation·G J RinkelE F Wijdicks
May 1, 1996·Acta Neurologica Scandinavica·A KaimW Steinbrich
Dec 4, 1998·Stroke; a Journal of Cerebral Circulation·E F WijdicksG M Miller
Nov 30, 1999·Critical Reviews in Neurosurgery : CR·J McMahon, N Dorsch
Feb 7, 2001·Brain : a Journal of Neurology·J van Gijn, G J Rinkel
Dec 4, 2003·Clinical Neurology and Neurosurgery·Joji InamasuKiyoshi Ichikizaki
Dec 29, 2007·Neurosurgery·Andrew S LittleRobert F Spetzler
Jul 12, 2008·Surgical Neurology·Sunil K GuptaSuresh N Mathuriya
May 25, 2011·Neurosurgical Review·Marco FontanellaAlessandro Ducati
Dec 27, 2011·Neurological Research·Homajoun MaslehatyHubertus Maximilian Mehdorn
Dec 5, 2012·Journal of Cerebrovascular and Endovascular Neurosurgery·Dong-Woo YuChul-Hoon Chang
Dec 24, 2013·Clinical Radiology·J WoodfieldJ V Byrne
Aug 21, 2014·Surgical Neurology International·Rajan KumarSanjay Behari
Nov 12, 2014·JAMA : the Journal of the American Medical Association·Ziad ObermeyerDavid M Cutler
Dec 20, 2014·Stroke; a Journal of Cerebral Circulation·Vivek B KalraAjay Malhotra
Sep 17, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Beatrice CannetiJosé Vivancos

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Citations

Nov 5, 2020·Journal of Neurosciences in Rural Practice·Girish Menon
Nov 23, 2021·Journal of Postgraduate Medicine·N Kumar, S Gupta

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