Radiomics Analysis Based on Multiparametric MRI for Predicting Early Recurrence in Hepatocellular Carcinoma After Partial Hepatectomy.

Journal of Magnetic Resonance Imaging : JMRI
Ying ZhaoAilian Liu

Abstract

Preoperative prediction of early recurrence (ER) of hepatocellular carcinoma (HCC) plays a critical role in individualized risk stratification and further treatment guidance. To investigate the role of radiomics analysis based on multiparametric MRI (mpMRI) for predicting ER in HCC after partial hepatectomy. Retrospective. In all, 113 HCC patients (ER, n = 58 vs. non-ER, n = 55), divided into training (n = 78) and validation (n = 35) cohorts. 1.5T or 3.0T, gradient-recalled-echo in-phase T1 -weighted imaging (I-T1 WI) and opposed-phase T1 WI (O-T1 WI), fast spin-echo T2 -weighted imaging (T2 WI), spin-echo planar diffusion-weighted imaging (DWI), and gradient-recalled-echo contrast-enhanced MRI (CE-MRI). In all, 1146 radiomics features were extracted from each image sequence, and radiomics models based on each sequence and their combination were established via multivariate logistic regression analysis. The clinicopathologic-radiologic (CPR) model and the combined model integrating the radiomics score with the CPR risk factors were constructed. A nomogram based on the combined model was established. Receiver operating characteristic (ROC) curve analysis was used to evaluate the discriminative performance of each model. The pote...Continue Reading

References

Oct 1, 2009·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Francesco D'AmicoUmberto Cillo
Nov 26, 2014·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Zhangjun ChengFeng Shen
Sep 26, 2015·Surgical Oncology·Gian Piero GuerriniMichele Colledan
Nov 12, 2015·World Journal of Gastroenterology : WJG·Yoav LurieGerardo Z Lederkremer
Nov 19, 2015·Radiology·Robert J GilliesHedvig Hricak
Jan 9, 2018·Lancet·Alejandro FornerJordi Bruix
Jun 23, 2018·World Journal of Gastroenterology : WJG·Davide IppolitoRiccardo Faletti
Aug 18, 2018·European Radiology·Kumar SandrasegaranMark Tann
Jan 11, 2019·Polish journal of radiology·Grzegorz RosiakAndrzej Cieszanowski
Feb 28, 2019·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Sungwon KimJin-Young Choi
Mar 1, 2019·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Quan-Yuan ShanMing Kuang
Apr 11, 2019·The New England Journal of Medicine·Augusto Villanueva
Apr 28, 2019·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Chunwang YuanJiliang Feng
May 16, 2019·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Zhen ZhangBin Song
Jul 3, 2019·Seminars in Liver Disease·Jordi Rimola
Jul 17, 2019·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Li ZhaoXinming Zhao

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Citations

May 11, 2021·World Journal of Gastroenterology : WJG·Jia-Sheng CaoXiu-Jun Cai
Aug 14, 2021·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Xiaonan MaoZaiming Lu

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