PMID: 9420796May 1, 1995Paper

Radionuclide assessment of myocardial fatty acid metabolism by PET and SPECT

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
N TamakiJ Konishi

Abstract

Although fatty acid is a major energy source in the normal myocardium, fatty acid oxidation is easily suppressed in a variety of cardiac disorders. Therefore assessment of fatty acid metabolism may hold an important role for early detection of myocardial abnormalities and provide insights into cardiac pathologic states. C-11 palmitate is a well-established PET tracer to probe myocardial fatty acid metabolism. On the other hand, a variety of iodinated fatty acid compounds have been introduced for assessment of fatty acid metabolism with conventional gamma cameras. These include straight-chain, such as iodopheyl pentadecanoic acid (IPPA), and branch-chain fatty acid compounds, such as beta-methyl iodopheyl pentadecanoic acid (BMIPP). This review article includes the characterization of these tracers and clinical experiences with these tracers for detection and characterizing patients with ischemic heart disease and cardiomyopathy.

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Citations

Dec 7, 2000·Annals of Nuclear Medicine·E TsujimuraT Nishimura
May 1, 1997·Annals of Nuclear Medicine·N TamakiJ Konishi
Feb 14, 1998·Annals of Nuclear Medicine·T MochizukiN Tamaki
Nov 18, 2010·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Nagara Tamaki, Keiichiro Yoshinaga
Sep 2, 2008·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Akira SatoMichiaki Hiroe
Mar 12, 2003·Journal of the American College of Cardiology·Satoshi KurisuHikaru Sato
Oct 18, 2000·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·D M Lambert
Jun 19, 2001·Neuromuscular Disorders : NMD·M MomoseS Inaba
Mar 17, 2001·Current Problems in Cardiology·D S BermanG Germano
Feb 3, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Masanao NayaNagara Tamaki
Nov 29, 2013·Journal of Labelled Compounds & Radiopharmaceuticals·B LångströmY Watanabe

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