PMID: 9637275Jun 24, 1998Paper

Radionuclide cancer therapy

Annals of Nuclear Medicine
C A Hoefnagel

Abstract

Therapeutic nuclear medicine is rapidly developing as an additional treatment modality in oncology. Its unique characteristics are the systemic, yet selective delivery of radiation doses in target tissues, its non-invasiveness, the relative lack of immediate and late side effects, and the advantage that uptake and retention in the tumor can be pre-assessed by tracer studies. Many different tumor seeking radiopharmaceuticals are being used for therapy by different routes and a variety of targeting mechanisms. The current clinical role of radionuclide therapy is briefly reviewed, as well as more general aspects and considerations, such as mechanisms for tumor targeting, the choice of radionuclide labels, radiopharmacy, drug delivery, radiation protection, dosimetry and toxicity.

References

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Citations

Mar 22, 2003·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Jörgen CarlssonJan Tennvall
Aug 22, 2006·Cancer Biotherapy & Radiopharmaceuticals·Emad F AzizRüdiger Lawaczeck
Feb 6, 2013·Theranostics·Brian T LukLiangfang Zhang
Sep 1, 2004·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Fernanda MarquesIsabel Santos
Jan 6, 2010·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·William Thomas PhillipsAnde Bao
Oct 9, 2014·Journal of Zhejiang University. Science. B·Chai-Hong YeongKwan-Hoong Ng
Jan 1, 2011·Cancers·Devrim ErsahinDavid Cheng
Jul 25, 2012·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Annamaria Pratelli, Paschalina Moschidou
Jun 3, 2009·Dalton Transactions : an International Journal of Inorganic Chemistry·Sara LacerdaIsabel Santos
Apr 11, 2006·Radiation Protection Dosimetry·Fernanda MarquesIsabel Santos
Mar 9, 2021·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·F K Amanuel
Oct 2, 2021·Advanced Materials·Yang LiuHongjie Zhang

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