Radionuclide imaging study of long-term pulmonary function after lobectomy in children with congenital cystic lung disease

Journal of Pediatric Surgery
Koji KomoriTomoo Miyakawa

Abstract

We evaluated the long-term pulmonary function after lobectomy for congenital cystic lung disease, in both infants and children, using radionuclide imaging (RI). We performed a retrospective review of 93 patients who underwent resection of cystic lung lesions between 1974 and 2001. The results of postoperative lung volume/perfusion scintigraphy at 1 (n = 64), 5 (n = 32), and 10 years (n = 18) after surgery (V1, 5, 10/Q1, 5, 10) and mean transit time (MTT-a marker for air-trapping) at 1, 5, and 10 years after surgery (MTT1, 5, 10) were compared with respect to age at operation, preoperative infection, underlying disease, and type of surgery. Patients who were younger than 1 year at the time of surgery showed a significantly lower MTT5 (1.09 +/- 0.08) and MTT10 (1.15 +/- 0.11) than patients who were older than 1 year at the time of surgery (MTT5, 1.49 +/- 0.67; MTT10, 1.54 +/- 0.33). The noninfected group had significantly higher Q10 and lower MTT10 values (P < .05) compared to the infected group. No significant differences were observed between patients with single lobe vs multiple lobe resection. The optimal age for surgery in patients with congenital cystic lung disease appears to be less than 1 year.

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Citations

Dec 3, 2014·Seminars in Pediatric Surgery·Robert BairdJean-Martin Laberge
Dec 10, 2013·Journal of the American College of Surgeons·Shaun M KunisakiRonald B Hirschl
Jun 12, 2012·Clinics in Perinatology·Pramod S Puligandla, Jean-Martin Laberge
Sep 6, 2011·Radiologic Clinics of North America·Frederick D Grant, S Ted Treves
Oct 6, 2010·Seminars in Nuclear Medicine·Paul J RoachDale L Bailey
May 28, 2011·Journal of Pediatric Surgery·Alana BeresPramod Puligandla
Jun 14, 2016·Journal of Pediatric Surgery·Amy E WagenaarEduardo A Perez
Aug 8, 2018·Pediatric Surgery International·Hisako KuyamaMayumi Yamamoto
Jul 6, 2019·European Journal of Nuclear Medicine and Molecular Imaging·Ora IsraelF Giammarile
Aug 25, 2020·Indian Journal of Thoracic and Cardiovascular Surgery : Official Organ, Association of Thoracic and Cardiovascular Surgeons of India·Mohamed ElShabrawy SalehMohammed Sanad
Mar 16, 2017·Pediatric Surgery International·Katrina J SullivanAhmed Nasr
Sep 28, 2017·Journal of Pediatric Surgery·Francesca TocchioniAntonio Messineo

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